Ortiz Karin Zazo, Bertolucci Paulo Henrique Ferreira
Departamento de Neurologia e Neurocirurgia da Universidade Federal de São Paulo - Escola Paulista de Medicina, São Paulo SP, Brasil.
Arq Neuropsiquiatr. 2005 Jun;63(2A):311-7. doi: 10.1590/s0004-282x2005000200020.
Alzheimer disease (AD) is usually associated with cognitive, language and behavioral impairments, which can get more and more serious as the disease progresses. The aim of this study is to verify language disorders in the early stages of this disease. Twelve patients meeting criteria for problable AD were evaluated by the Boston test, and all of them scored more than 23 points on the Mini-Mental State Examination. Data acquired on this language evaluation were compared with the average of normal population data. All patients showed language disorders. Statistical differences were found in visual confrontating naming and auditory comphrension tasks. The patients performed well in writing and reading tasks. We believe that there might have had an interference in the patient's linguistic task performance due to their memory impairment. We could find language impairments in the early stages of AD.
阿尔茨海默病（AD）通常与认知、语言和行为障碍相关，随着疾病进展，这些障碍会越来越严重。本研究的目的是验证该疾病早期阶段的语言障碍。12名符合可能AD标准的患者通过波士顿测试进行评估，且他们在简易精神状态检查表上的得分均超过23分。将此次语言评估获得的数据与正常人群数据的平均值进行比较。所有患者均表现出语言障碍。在视觉面对命名和听觉理解任务中发现了统计学差异。患者在书写和阅读任务中表现良好。我们认为，由于患者的记忆障碍，可能对其语言任务表现产生了干扰。我们能够在AD的早期阶段发现语言障碍。
