Zhang Yu, Chen Yinyan, Hu Yuntong, Huang Fang, Xiao Yuhong
The Affiliated Stomatological Hospital of Kunming Medical University.
Department of Stomatology, Kunming General Hospital of Chengdu Military Command, Teaching Hospital of Kunming Medical University.
Dent Mater J. 2018 Mar 30;37(2):183-191. doi: 10.4012/dmj.2017-096. Epub 2017 Dec 8.
Quaternary ammonium compounds (QACs) have been used widely in medicine, owing to their antimicrobial properties. They also have strong permeability, stable performance, low skin irritation, low toxicity, low corrosion, lasting biological effects and so on, comparing with other antimicrobial agents. At the end of last century, polymerizable quaternary ammonium antimicrobial monomers had been synthesized and applied in dentistry, in order to reduce or prevent microbial biofilm formation on dental materials surfaces. This review aims to discuss the current progress of QACs applied in composite resin, adhesive systems, acrylic resin, glass ionomer cement and endodontic materials, regarding to their antimicrobial potential, mechanical properties, and biocompatibility.
季铵化合物（QACs）因其抗菌特性而在医学中得到广泛应用。与其他抗菌剂相比，它们还具有强渗透性、性能稳定、对皮肤刺激性低、毒性低、腐蚀性低、生物效应持久等特点。上世纪末，可聚合季铵抗菌单体已被合成并应用于牙科领域，以减少或防止牙科材料表面微生物生物膜的形成。本综述旨在探讨QACs在复合树脂、粘结系统、丙烯酸树脂、玻璃离子水门汀和牙髓材料中的应用现状，涉及它们的抗菌潜力、机械性能和生物相容性。
