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2%洗必泰凝胶、氢氧化钙和中药根管内药物对粪肠球菌的牙本质小管消毒作用:一项体外研究。

Disinfection of dentinal tubules with 2% Chlorhexidine gel, Calcium hydroxide and herbal intracanal medicaments against Enterococcus faecalis: An in-vitro study.

作者信息

Vasudeva Agrima, Sinha Dakshita Joy, Tyagi Shashi Prabha, Singh Narendra Nath, Garg Paridhi, Upadhyay Deepti

机构信息

Department of Conservative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh 244001, India.

Department of Conservative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh 244001, India.

出版信息

Singapore Dent J. 2017 Dec;38:39-44. doi: 10.1016/j.sdj.2017.06.001.

Abstract

AIM

This in vitro study was conducted to evaluate the disinfection of dentinal tubules using 2% Chlorhexidine gel, Honey, Aloe vera gel, Curcuma longa, Propolis gel and Calcium hydroxide against Enterococcus faecalis.

MATERIALS AND METHOD

Two hundred and ten human mandibular first premolars were infected with Enterococcus faecalis for 21 days. Samples were divided into 7 groups. Group I- Saline (negative control), Group II- 2% Chlorhexidine gel(CHX), Group III- honey, Group IV- Aloe vera gel, Group V- 20% Curcuma longa gel, Group VI- Propolis gel and Group VII -Calcium hydroxide (CH). At the end of 1, 3 and 5 days, the antimicrobial efficacy of medicaments against E.faecalis was assessed at the depths of 200µm and 400µm.

RESULTS

2% Chlorhexidine gel was most effective followed by Propolis and Curcuma longa.

CONCLUSION

2% Chlorhexidine gel gave the best results. Among the herbal extracts Propolis and Curcuma longa hold a promising future but to implement their use as sole intracanal medicaments clinically, further in vivo and long term studies are warranted.

摘要

目的

本体外研究旨在评估2%氯己定凝胶、蜂蜜、芦荟凝胶、姜黄、蜂胶凝胶和氢氧化钙对粪肠球菌的牙本质小管消毒效果。

材料与方法

将210颗人下颌第一前磨牙感染粪肠球菌21天。样本分为7组。第一组-生理盐水(阴性对照),第二组-2%氯己定凝胶(CHX),第三组-蜂蜜,第四组-芦荟凝胶,第五组-20%姜黄凝胶,第六组-蜂胶凝胶,第七组-氢氧化钙(CH)。在第1、3和5天结束时,在200μm和400μm深度评估药物对粪肠球菌的抗菌效果。

结果

2%氯己定凝胶最有效,其次是蜂胶和姜黄。

结论

2%氯己定凝胶效果最佳。在草药提取物中,蜂胶和姜黄前景广阔,但要在临床上将其作为唯一的根管内药物使用,还需要进一步的体内和长期研究。

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