Time-Dependent Antibacterial Effects of Seed Extract Compared to Calcium Hydroxide in Teeth Infected with .

STATEMENT OF THE PROBLEM

Endodontic efforts are focused on eliminating intracanal pathogens. Applying intracanal medicament for infected teeth is beneficial for achieving better antibacterial effects in endodontic treatments. Different intracanal medicaments should be assessed and compared for this purpose.

PURPOSE

The aim of this study was to assess the antibacterial efficacy of seed extract comparing to Ca(OH) on teeth contaminated with .

MATERIALS AND METHOD

In this study, a novel strain of ( ATCC 19433) yielded from the root canal treated tooth with persistent apical periodontitis. The canals of 78 human single-rooted extracted teeth were contaminated with mentioned strain and treated with essential oil and Ca(OH) for 1, 7, and 14 days. To determine the chemical composition of the oils, gas chromatography-mass spectrometry (GC-MS) was applied. The percentage reduction from baseline c.f.u./mL values was estimated.

RESULTS

Oleic acid, benzoic acid, and gallic acid were the major contents of essential oil. The c.f.u./mL count decreased considerably as contact duration rose for both medicaments. After 7 days, a statistically significant difference was identified between the medicaments. showed higher antimicrobial efficacy. However, after 14 days, no substantial difference was found.

CONCLUSION

essential oil, displayed great antimicrobial efficacy against higher than Ca(OH) over the first week contact period.