对印度抑郁症患者血浆脂肪酸的对照研究。
A controlled study of plasma fatty acids in Indian patients with depressive episode.
机构信息
Department of Psychiatry, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India.
Department of Psychiatry, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India.
出版信息
Asian J Psychiatr. 2018 Jan;31:152-156. doi: 10.1016/j.ajp.2017.12.006. Epub 2017 Dec 8.
AIM
To study the plasma omega 3 and omega 6 fatty acid levels in patients with depressive episode and in matched healthy controls.
METHOD
Thirty patients with first episode depression and thirty healthy matched control subjects were recruited from a tertiary care hospital setting. We measured plasma omega-3 and omega-6 fatty acid levels of the study and the control group.
RESULT
There were no significant differences in plasma omega 3 fatty acid levels between study group and control group. The plasma omega 6 fatty acid levels of study group were significantly less than that of control group.
CONCLUSIONS
The present study is an initial attempt to investigate the link between fatty acids and depression in a clinical setting in India. This comparative study with normal controls did not etiologically link these polyunsaturated fatty acids in this sample of depressive disorder.
目的
研究抑郁发作患者与匹配健康对照者的血浆ω-3 和 ω-6 脂肪酸水平。
方法
从一家三级护理医院中招募了 30 例首发抑郁症患者和 30 例健康匹配对照者。我们测量了研究组和对照组的血浆 ω-3 和 ω-6 脂肪酸水平。
结果
研究组与对照组之间的血浆 ω-3 脂肪酸水平无显著差异。研究组的血浆 ω-6 脂肪酸水平显著低于对照组。
结论
本研究首次尝试在印度的临床环境中研究脂肪酸与抑郁症之间的关系。这项与正常对照组的比较研究并未在这例抑郁障碍样本中从病因学上联系这些多不饱和脂肪酸。
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