哈巴尼特孤立群体中足弓的连锁分析与遗传
Linkage analysis and the inheritance of arches in a Habbanite isolate.
作者信息
Anderson M W, Bonné-Tamir B, Carmelli D, Thompson E A
出版信息
Am J Hum Genet. 1979 Sep;31(5):620-9.
Abstract
A pedigree and linkage analysis was performed on a corrected version of the Habbanite pedigree 2 of Slatis et al. [1]. The trait "arch on any digit" was examined for major gene inheritance and possible linkage to several blood and serum group markers. The results confirm the proposed dominant major gene inheritance of this trait with almost complete penetrance. In addition, the analysis suggests linkage with the haptoglobin locus with evidence against linkage with Pl and Rhesus. These results are of particular interest in view of recently reported dermatoglyphic associations with haptoglobin.
摘要
对斯拉蒂斯等人[1]的哈巴尼特系谱2的校正版本进行了系谱和连锁分析。研究了“任何手指上的弓纹”这一性状的主基因遗传情况以及与几种血型和血清型标记的可能连锁关系。结果证实了该性状的显性主基因遗传，且几乎完全外显。此外，分析表明与触珠蛋白基因座存在连锁关系，同时有证据表明与Pl和恒河猴血型不存在连锁关系。鉴于最近报道的皮纹与触珠蛋白的关联，这些结果特别令人关注。
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本文引用的文献
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A general model for the genetic analysis of pedigree data.家系数据遗传分析的通用模型。
Hum Hered. 1971;21(6):523-42. doi: 10.1159/000152448.
2
The Habbanite isolate. II. Digital and palmar dermatoglyphics.哈巴奈特分离株。二、手指和手掌皮肤纹理学
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The inheritance of fingerprint patterns.指纹图案的遗传。
Am J Hum Genet. 1976 May;28(3):280-9.
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