Kjolhede C L, Gadomski A M, Wittpenn J, Bulux J, Rosas A R, Solomons N W, Brown K H, Forman M R
Department of International Health, Johns Hopkins University, Baltimore, MD.
Am J Clin Nutr. 1989 Mar;49(3):490-4. doi: 10.1093/ajcn/49.3.490.
Two hundred and thirty-six Guatemalan children aged 2-14 y were examined for subclinical vitamin A deficiency by use of conjunctival impression cytology (CIC). The feasibility of the technique and quality of a modified touch procedure were assessed. Neither lid speculum nor physical restraint in the form of a papoose board was used. The CIC technique was easily performed on children aged greater than 3 y but was more difficult among those less than or equal to 3 y. Laboratory processing of specimens is uncomplicated but interpretation may be problematic and requires clearly defined criteria of normal and abnormal cytology as well as careful standardization of readers.
对236名年龄在2至14岁的危地马拉儿童使用结膜印迹细胞学（CIC）方法检查亚临床维生素A缺乏情况。评估了该技术的可行性以及改良触摸程序的质量。未使用眼睑撑开器，也未采用婴儿固定板形式的身体约束。CIC技术在3岁以上儿童中易于操作，但在3岁及以下儿童中操作更困难。标本的实验室处理并不复杂，但解读可能存在问题，需要明确界定正常和异常细胞学的标准以及仔细规范阅片者。
