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北海獭(Enhydra lutris kenyoni)的基因组

The Genome of the Northern Sea Otter (Enhydra lutris kenyoni).

作者信息

Jones Samantha J, Haulena Martin, Taylor Gregory A, Chan Simon, Bilobram Steven, Warren René L, Hammond S Austin, Mungall Karen L, Choo Caleb, Kirk Heather, Pandoh Pawan, Ally Adrian, Dhalla Noreen, Tam Angela K Y, Troussard Armelle, Paulino Daniel, Coope Robin J N, Mungall Andrew J, Moore Richard, Zhao Yongjun, Birol Inanc, Ma Yussanne, Marra Marco, Jones Steven J M

机构信息

Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 4E6, Canada.

Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.

出版信息

Genes (Basel). 2017 Dec 11;8(12):379. doi: 10.3390/genes8120379.

DOI:10.3390/genes8120379
PMID:29232880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5748697/
Abstract

The northern sea otter inhabits coastal waters of the northern Pacific Ocean and is the largest member of the Mustelidae family. DNA sequencing methods that utilize microfluidic partitioned and non-partitioned library construction were used to establish the sea otter genome. The final assembly provided 2.426 Gbp of highly contiguous assembled genomic sequences with a scaffold N50 length of over 38 Mbp. We generated transcriptome data derived from a lymphoma to aid in the determination of functional elements. The assembled genome sequence and underlying sequence data are available at the National Center for Biotechnology Information (NCBI) under the BioProject accession number PRJNA388419.

摘要

北海獭栖息于北太平洋的沿海水域,是鼬科家族中体型最大的成员。利用微流控分区和非分区文库构建的DNA测序方法来构建海獭基因组。最终组装得到了2.426 Gbp的高度连续组装基因组序列,支架N50长度超过38 Mbp。我们从淋巴瘤中生成了转录组数据,以帮助确定功能元件。组装好的基因组序列和基础序列数据可在国家生物技术信息中心(NCBI)获取,生物项目登录号为PRJNA388419。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d00/5748697/b22d3191171b/genes-08-00379-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d00/5748697/5c765643016d/genes-08-00379-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d00/5748697/b22d3191171b/genes-08-00379-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d00/5748697/5c765643016d/genes-08-00379-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d00/5748697/b22d3191171b/genes-08-00379-g002.jpg

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