Javed F, Kellesarian S V, Abduljabbar T, Abduljabbar A T, Akram Z, Vohra F, Rahman I, Romanos G E
Department of General Dentistry, Eastman Institute for Oral Health University of Rochester, NY, USA.
Department of General Dentistry, Eastman Institute for Oral Health University of Rochester, NY, USA.
Int J Oral Maxillofac Surg. 2018 Jun;47(6):764-772. doi: 10.1016/j.ijom.2017.11.009. Epub 2017 Dec 9.
There are no studies that have systematically reviewed the influence of involuntary cigarette smoke inhalation (ICSI) on the stability of implants. The aim of the present study was to perform a systematic review and meta-analysis of preclinical studies that assessed the influence of involuntary cigarette smoke inhalation ICSI on osseointegration. Indexed databases (PubMed, Google-Scholar, Scopus, EMBASE, and Web of Knowledge) were searched till September 2017. Titles and abstracts of studies identified using the above-described protocol were independently screened by 2 authors. Full-texts of studies judged by title and abstract to be relevant were independently evaluated for the stated eligibility criteria. Nine studies were included. Six studies showed that ICSI compromised bone area contact around implants. In 4 studies, peri-implant bone mineral density was significantly higher in the control group than among subjects exposed to ICSI. For the effects of ICSI on the osseointegration of dental implants, significant differences could be observed for bone-to-implant contact for test subjects in cancellous (Z=-4.08, p<0.001) and cortical bone (Z=-4.31, p<0.001) respectively. ICSI may negatively influence osseointegration of dental implants. It is imperative to educate patients about the negative effects of passive smoking on dental and systemic health.
尚无研究系统评价非自愿吸入香烟烟雾（ICSI）对种植体稳定性的影响。本研究的目的是对评估非自愿吸入香烟烟雾（ICSI）对骨结合影响的临床前研究进行系统评价和荟萃分析。检索了截至2017年9月的索引数据库（PubMed、谷歌学术、Scopus、EMBASE和Web of Knowledge）。由两名作者独立筛选使用上述方案确定的研究的标题和摘要。对标题和摘要判断为相关的研究全文，根据规定的纳入标准进行独立评估。共纳入9项研究。6项研究表明，ICSI会损害种植体周围的骨接触面积。在4项研究中，对照组的种植体周围骨密度显著高于暴露于ICSI的受试者。对于ICSI对牙种植体骨结合的影响，在松质骨（Z=-4.08，p<0.001）和皮质骨（Z=-4.31，p<0.001）中，试验对象的骨与种植体接触存在显著差异。ICSI可能会对牙种植体的骨结合产生负面影响。必须告知患者被动吸烟对牙齿和全身健康的负面影响。
