Changwei Ren, Sun Lizhong, Xu Shangdong, Lai Yongqiang
Department of Cardiovascular Surgery Center, Capital Medical University, Beijing Anzhen Hospital, Beijing, China.
J Card Surg. 2017 Dec;32(12):817-821. doi: 10.1111/jocs.13505. Epub 2017 Dec 12.
This study aims to evaluate the results of one-stage ascending-to-abdominal aortic bypass and aortic valve replacement for concomitant aortic coarctation combined with aortic valve pathology.
From June 2009 to March 2017, 28 consecutive adult patients (23 males and five females) with aortic coarctation combined with aortic valve pathology underwent one-stage ascending-to-abdominal aorta bypass and aortic valve replacement or a Bentall procedure. Patients were followed for a mean of 45.5 ± 26.5 months (range 3-96 months).
All patients successfully underwent the one-stage procedure. No early deaths were recorded. The mean aortic cross-clamp and cardiopulmonary bypass times were 71 ± 23 and 113 ± 37 mins, respectively. Re-exploration for bleeding was performed on one patient (3.6%). The average post-operative hospital stay was 15.9 ± 4.9 days and the average operation time was 5.2 h. No paraplegia or stroke was observed. The blood pressure gradient of the upper and lower extremities significantly decreased (P < 0.001). Systolic blood pressure decreased from 158 ± 36 mmHg pre-operatively to 121 ± 18 mmHg post-operatively. No deaths or significant gradients between the upper and lower extremities occurred during follow-up. No death and complications of bypass grafts occurred during follow-up.
Ascending-to-abdominal aortic bypass and concomitant aortic valve procedures are a suitable therapeutic option for severe aortic coarctation combined with aortic valve pathology in adult patients.
本研究旨在评估一期升主动脉至腹主动脉旁路移植术联合主动脉瓣置换术治疗主动脉缩窄合并主动脉瓣病变的效果。
2009年6月至2017年3月,28例连续的成年主动脉缩窄合并主动脉瓣病变患者(23例男性,5例女性)接受了一期升主动脉至腹主动脉旁路移植术联合主动脉瓣置换术或Bentall手术。患者平均随访45.5±26.5个月(范围3 - 96个月)。
所有患者均成功完成一期手术。无早期死亡病例记录。平均主动脉阻断时间和体外循环时间分别为71±23分钟和113±37分钟。1例患者(3.6%)因出血进行了再次手术探查。术后平均住院时间为15.9±4.9天,平均手术时间为5.2小时。未观察到截瘫或中风。上下肢血压梯度显著降低(P<0.001)。收缩压从术前的158±36mmHg降至术后的121±18mmHg。随访期间未发生死亡或上下肢明显梯度异常。随访期间未发生旁路移植物相关死亡和并发症。
升主动脉至腹主动脉旁路移植术联合主动脉瓣手术是成年严重主动脉缩窄合并主动脉瓣病变患者的合适治疗选择。