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宠物饲养与衰老生物标志物的关联:基于人群的队列研究。

Associations of pet ownership with biomarkers of ageing: population based cohort study.

作者信息

Batty G David, Zaninotto Paola, Watt Richard G, Bell Steven

机构信息

Department of Epidemiology and Public Health, University College, London, UK

Department of Epidemiology and Public Health, University College, London, UK.

出版信息

BMJ. 2017 Dec 13;359:j5558. doi: 10.1136/bmj.j5558.

Abstract

OBJECTIVE

To examine the prospective relation between animal companionship and biomarkers of ageing in older people.

DESIGN

Analyses of data from the English Longitudinal Study of Ageing, an ongoing, open, prospective cohort study initiated in 2002-03.

SETTING

Nationally representative study from England.

PARTICIPANTS

8785 adults (55% women) with a mean age of 67 years (SD 9) at pet ownership assessment in 2010-11 (wave 5).

MAIN OUTCOME MEASURE

Established biomarkers of ageing in the domains of physical, immunological, and psychological function, as assessed in 2012-13 (wave 6).

RESULTS

One third of study members reported pet ownership: 1619 (18%) owned a dog, 1077 (12%) a cat, and 274 (3%) another animal. After adjustment for a range of covariates, there was no evidence of a clear association of any type of pet ownership with walking speed, lung function, chair rise time, grip strength, leg raises, balance, three markers of systemic inflammation, memory, or depressive symptoms.

CONCLUSION

In this population of older adults, the companionship of creatures great and small seems to essentially confer no relation with standard ageing phenotypes.

摘要

目的

研究老年人中动物陪伴与衰老生物标志物之间的前瞻性关系。

设计

对英国老龄化纵向研究的数据进行分析,该研究是一项于2002 - 2003年启动的正在进行的、开放的前瞻性队列研究。

背景

来自英国的全国代表性研究。

参与者

2010 - 2011年(第5轮)进行宠物拥有情况评估时,8785名成年人(55%为女性),平均年龄67岁(标准差9)。

主要观察指标

2012 - 2013年(第6轮)评估的身体、免疫和心理功能领域中已确定的衰老生物标志物。

结果

三分之一的研究成员报告拥有宠物:1619人(18%)养狗,1077人(12%)养猫,274人(3%)养其他动物。在对一系列协变量进行调整后,没有证据表明任何类型的宠物拥有情况与步行速度、肺功能、从椅子上起身时间、握力、抬腿、平衡、全身炎症的三个标志物、记忆力或抑郁症状之间存在明显关联。

结论

在这群老年人中,无论大小动物的陪伴似乎与标准衰老表型基本无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce3/5728306/ae1ff827492b/batd036533.f1.jpg

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