Wassay Shaikh Ahmed Muntajib, Dar Farhan Javed, Saleh Asem K, Mansoor Ibrahim
International Medical Center, Jeddah, Saudi Arabia.
Laboratory Medicine & Blood Bank, P.O. Box 2172, Jeddah 21451, Saudi Arabia.
Ther Adv Endocrinol Metab. 2017 Dec;8(12):169-172. doi: 10.1177/2042018817739571. Epub 2017 Nov 2.
Hypertriglyceridemia of obesity, the metabolic syndrome, and type II diabetes mellitus are highly prevalent in Saudi Arabia. Severe hypertriglyceridemia is a rare but well known cause of acute pancreatitis. In treatment pancreatic rest, lifestyle changes, and lipid-lowering medications are essential, but the response is slow. Recently the role of therapeutic plasma exchange (TPE) has been stressed for fast and effective management in addition to insulin and heparin infusion. TPE for hypertriglyceridemic pancreatitis resulted in drastic improvements in clinical and laboratory findings and patient outcomes as suggested in our cases. However, this procedure is limited due to its high cost and availability only in specialized hospitals.
肥胖、代谢综合征和II型糖尿病引起的高甘油三酯血症在沙特阿拉伯极为普遍。严重的高甘油三酯血症是急性胰腺炎的一种罕见但广为人知的病因。在治疗中，胰腺休息、生活方式改变和降脂药物至关重要，但反应缓慢。最近，除了输注胰岛素和肝素外，治疗性血浆置换（TPE）在快速有效管理方面的作用也得到了强调。正如我们的病例所示，TPE治疗高甘油三酯血症性胰腺炎可使临床和实验室检查结果以及患者预后得到显著改善。然而，该程序由于成本高昂且仅在专科医院可用而受到限制。
