Li Ting, Wu Xiu-Juan, Chen Xiao-Min, Wang Si-Bo, Liu Kang-Ding, Xing Ying-Qi
Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, Jilin Province, China.
Neural Regen Res. 2017 Nov;12(11):1853-1859. doi: 10.4103/1673-5374.219046.
The incidence of ischemic stroke in patients with diabetes is increasing. While brachial-ankle pulse wave velocity (BaPWV) and ankle-brachial index (ABI) are known to be associated with ischemic cardiovascular and cerebrovascular diseases, whether these measures predict the risk of ischemic cerebrovascular disease in diabetic patients remains unclear. 117 patients with type 2 diabetes were enrolled in this study. According to the results of head magnetic resonance imaging, the patients were divided into a diabetes-only group (n = 55) and a diabetes and ischemic stroke group (n = 62). We then performed ABI and BaPWV examinations for all patients. Compared with the diabetes-only group, we found decreased ABI and increased BaPWV in the diabetes and ischemic stroke group. Multivariate logistic regression analyses revealed that BaPWV and ABI were risk factors for ischemic stroke in patients with type 2 diabetes. Our findings indicate that decreased ABI and increased BaPWV are objective indicators of increased risk of ischemic stroke in patients with type 2 diabetes.
糖尿病患者缺血性卒中的发病率正在上升。虽然已知肱踝脉搏波速度（BaPWV）和踝臂指数（ABI）与缺血性心血管和脑血管疾病有关，但这些指标是否能预测糖尿病患者缺血性脑血管疾病的风险仍不清楚。本研究纳入了117例2型糖尿病患者。根据头部磁共振成像结果，将患者分为单纯糖尿病组（n = 55）和糖尿病合并缺血性卒中组（n = 62）。然后我们对所有患者进行了ABI和BaPWV检查。与单纯糖尿病组相比，我们发现糖尿病合并缺血性卒中组的ABI降低，BaPWV升高。多因素逻辑回归分析显示，BaPWV和ABI是2型糖尿病患者缺血性卒中的危险因素。我们的研究结果表明，ABI降低和BaPWV升高是2型糖尿病患者缺血性卒中风险增加的客观指标。
