[高度分散铜粉对实验性心肌梗死中超氧化物歧化酶和谷胱甘肽过氧化物酶活性的影响]
[Effect of a highly dispersed copper powder on superoxide dismutase and glutathione peroxidase activities in experimental myocardial infarct].
作者信息
Konovalova G G, Lankin V Z, Bogoslovskaia O A, Glushchenko N N, Fedorov Iu I
出版信息
Biull Eksp Biol Med. 1989 Feb;107(2):154-7.
PMID:2923968
Abstract
Administration of highly dispersed copper powder in a dose 0.2 mg/kg three days before modelled coronary-occlusion myocardial infarction caused transitory increase in activity of antioxidant enzymes--superoxide dismutase and glutathione peroxidase in the necrotic zone of myocardium of rats, and also staunch increase in the activity of these enzymes in noninfarction region.
摘要
在模拟冠状动脉闭塞性心肌梗死前三日，以0.2毫克/千克的剂量给予高度分散的铜粉，可使大鼠心肌梗死坏死区抗氧化酶——超氧化物歧化酶和谷胱甘肽过氧化物酶的活性暂时升高，并且还能使这些酶在非梗死区域的活性显著增加。
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