Yamamoto Masateru, Tahara Hiroyuki, Hamaoka Michinori, Shimizu Seiichi, Kuroda Shintaro, Ohira Masahiro, Ide Kentaro, Kobayashi Tsuyoshi, Ohdan Hideki
Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Science, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima City, Hiroshima 734-8551, Japan.
Int J Surg Case Rep. 2018;42:104-108. doi: 10.1016/j.ijscr.2017.12.010. Epub 2017 Dec 9.
Reflux cholangitis is a frequent complication of Roux-en-Y choledochojejunostomy.
A 68-year-old male underwent left lobectomy of the liver, bile duct resection and choledochojejunostomy for intrahepatic cholangiocarcinoma located in Segment 2 of the liver, 40mm in diameter with a lymph node metastasis 5 years ago. He had frequent recurrences of postoperative reflux cholangitis and hepatic abscesses and was treated with antibiotics each time. Postoperative adjuvant chemotherapy was scheduled, but due to recurrent cholangitis it was difficult. Although double balloon endoscopy for endoscopic retrograde cholangiography was performed, no stenosis was found in the choledochojejunostomy anastomosis, and no defect suspected of calculus and stenosis were found by contrast. Antibiotics had to be administered for a long time because it recurred when antibiotics were discontinued. This time, a tumor 2.0cm in diameter was detected in segment 7 of the liver on follow - up computed tomography. The preoperative diagnosis was recurrent Intrahepatic cholangiocarcinoma. Hepatobiliary scintigraphy was carried out in preparation for concomitant treatment of his reflux cholangitis. Retention in the blind loop of the choledochojejunostomy was retarded, and the excretion was delayed. Therefore, hepatectomy and resection of the blind loop were performed. We confirmed improvement of stasis in the blind loop on postoperative hepatobiliary scintigraphy. The postoperative course was uneventful, and antibiotics were not required.
Hepatobiliary scintigraphy may be able to clarify the mechanism underlying reflux cholangitis.
Hepatobiliary scintigraphy was useful for the treatment of recurrent reflux cholangitis in this case.
反流性胆管炎是Roux-en-Y胆总管空肠吻合术常见的并发症。
一名68岁男性5年前因位于肝脏第2段的直径40mm的肝内胆管癌伴淋巴结转移,接受了肝左叶切除术、胆管切除术及胆总管空肠吻合术。术后他频繁发生反流性胆管炎和肝脓肿复发,每次均接受抗生素治疗。术后计划进行辅助化疗,但由于胆管炎复发而难以实施。尽管进行了双气囊内镜逆行胆管造影,但在胆总管空肠吻合口未发现狭窄,造影也未发现疑似结石和狭窄的缺损。由于停用抗生素后病情复发,不得不长期使用抗生素。此次,在随访计算机断层扫描中发现肝脏第7段有一个直径2.0cm的肿瘤。术前诊断为复发性肝内胆管癌。为同时治疗其反流性胆管炎进行了肝胆闪烁显像。胆总管空肠吻合术盲袢内滞留延迟,排泄延迟。因此,进行了肝切除术及盲袢切除术。术后肝胆闪烁显像证实盲袢内淤滞改善。术后病程顺利,无需使用抗生素。
肝胆闪烁显像或许能够阐明反流性胆管炎的潜在机制。
在该病例中,肝胆闪烁显像对复发性反流性胆管炎的治疗有用。