Department of Urology, University of Washington School of Medicine, 1959 NE Pacific Street, Box 356510, Seattle, WA, 98195, USA.
Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, Seattle, WA, USA.
World J Urol. 2018 May;36(5):727-732. doi: 10.1007/s00345-017-2156-8. Epub 2017 Dec 14.
Posterior acoustic shadow width has been proposed as a more accurate measure of kidney stone size compared to direct measurement of stone width on ultrasound (US). Published data in humans to date have been based on a research using US system. Herein, we compared these two measurements in clinical US images.
Thirty patient image sets where computed tomography (CT) and US images were captured less than 1 day apart were retrospectively reviewed. Five blinded reviewers independently assessed the largest stone in each image set for shadow presence and size. Shadow size was compared to US and CT stone sizes.
Eighty percent of included stones demonstrated an acoustic shadow; 83% of stones without a shadow were ≤ 5 mm on CT. Average stone size was 6.5 ± 4.0 mm on CT, 10.3 ± 4.1 mm on US, and 7.5 ± 4.2 mm by shadow width. On average, US overestimated stone size by 3.8 ± 2.4 mm based on stone width (p < 0.001) and 1.0 ± 1.4 mm based on shadow width (p < 0.0098). Shadow measurements decreased misclassification of stones by 25% among three clinically relevant size categories (≤ 5, 5.1-10, > 10 mm), and by 50% for stones ≤ 5 mm.
US overestimates stone size compared to CT. Retrospective measurement of the acoustic shadow from the same clinical US images is a more accurate reflection of true stone size than direct stone measurement. Most stones without a posterior shadow are ≤ 5 mm.
与超声(US)上直接测量结石宽度相比,后向声影宽度已被提出作为更准确的肾结石大小测量方法。迄今为止,在人类中发表的数据基于使用 US 系统的研究。在此,我们比较了这两种在临床 US 图像上的测量方法。
回顾性分析了 30 例 CT 和 US 图像采集时间相差不到 1 天的患者图像集。5 名盲法评估者独立评估了每个图像集中最大的结石的阴影存在和大小。比较了阴影大小与 US 和 CT 结石大小。
80%的纳入结石显示有后向声影;83%无阴影的结石在 CT 上的大小为≤5mm。CT 上的平均结石大小为 6.5±4.0mm,US 上为 10.3±4.1mm,阴影宽度为 7.5±4.2mm。平均而言,US 基于结石宽度高估结石大小 3.8±2.4mm(p<0.001),基于阴影宽度高估结石大小 1.0±1.4mm(p<0.0098)。在三个临床相关的大小类别(≤5、5.1-10、>10mm)中,阴影测量法减少了 25%的结石分类错误,在≤5mm 的结石中减少了 50%。
与 CT 相比,US 高估了结石的大小。从相同的临床 US 图像中回顾性测量后向声影,比直接测量结石更能准确反映真实的结石大小。大多数无后向声影的结石为≤5mm。