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直径小于或等于10毫米结石的超声诊断价值及输尿管绞痛的临床放射学变异

Diagnostic value ultrasound signs of stones less than or equal to 10 mm and clinico-radiological variants of ureteric colic.

作者信息

Krakhotkin Denis V, Chernylovskyi Volodymyr A, Sarica Kemal, Tsaturyan Arman, Liatsikos Evangelos, Makevicius Jurijus, Iglovikov Nikolay Yu, Pikhovkin Dmitry N

机构信息

Central District Hospital, Outpatient Clinic, Sadovaya Lane 23, Kamenolomni, Rostov Region, Russia.

Private Urological Practice, Dnipro, Ukraine.

出版信息

Asian J Urol. 2023 Jan;10(1):39-49. doi: 10.1016/j.ajur.2022.03.015. Epub 2022 Nov 13.

DOI:10.1016/j.ajur.2022.03.015
PMID:36721697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9875159/
Abstract

OBJECTIVE

To determine the diagnostic value of ultrasound signs of urinary stones less than or equal to 10 mm and to determine clinico-radiological variants of ureteric colic.

METHODS

A total of 455 ultrasound investigations were performed in patients referring to emergency department with urolithiasis and symptoms suspected of ureteric colic between January 2021 and May 2021. In addition to microscopic evaluation of urine sediment to detect different crystals and non-contrast spiral computed tomography to detect stones, B-mode and color Doppler sonography was performed to assess the presence of acoustic shadow (AS) and twinkle artifacts (TA) as possible signs of stone(s) in ureter.

RESULTS

While the sensitivity and specificity of AS and TA were higher than 90% in patients with stones greater than 5 mm; positive prognostic values of these parameters were found to be extremely low for stones with sizes of 1-3 mm with specificity and sensitivity values not exceeding 53%. The sensitivity and specificity of AS and TA in the upper and lower ureters were higher for stones greater than or equal to 5 than for compared to those less than 5 mm. At the same time, the diagnostic values of TA and AS for middle ureter stones were very limited. The most prevalent clinico-radiological variants of ureteric colic were types I, III, and V being observed in 39%, 28% and 21% cases, respectively.

CONCLUSION

Our results demonstrate that TA and AS parameters seem to have a very low sensitivity and specificity in the diagnosis of urinary stones less than 5 mm. The diagnostic value of TA and AS increase significantly in stones greater than or equal to 5 mm. Therefore, clinicians need to be very careful for overestimating the diagnostic values of TA and AS for stones less than 5 mm and non-contrast spiral computed tomography must be the method of choice for patients presenting to emergency department with ureteric colic.

摘要

目的

确定直径小于或等于10毫米的尿路结石超声征象的诊断价值,并确定输尿管绞痛的临床放射学变异类型。

方法

2021年1月至2021年5月期间,对因尿石症到急诊科就诊且怀疑有输尿管绞痛症状的患者进行了455次超声检查。除了对尿沉渣进行显微镜检查以检测不同晶体以及进行非增强螺旋计算机断层扫描以检测结石外,还进行了B超和彩色多普勒超声检查,以评估声影(AS)和闪烁伪像(TA)的存在情况,作为输尿管结石的可能征象。

结果

对于直径大于5毫米的结石患者,AS和TA的敏感性和特异性均高于90%;而对于直径为1 - 3毫米的结石,这些参数的阳性预测值极低,特异性和敏感性值均不超过53%。对于直径大于或等于5毫米的结石,AS和TA在输尿管上段和下段的敏感性和特异性高于直径小于5毫米的结石。同时,TA和AS对输尿管中段结石的诊断价值非常有限。输尿管绞痛最常见的临床放射学变异类型为I型、III型和V型,分别见于39%、28%和21%的病例。

结论

我们的结果表明,TA和AS参数在诊断小于5毫米的尿路结石时敏感性和特异性似乎非常低。对于直径大于或等于5毫米的结石,TA和AS的诊断价值显著增加。因此,临床医生在高估TA和AS对小于5毫米结石的诊断价值时需格外谨慎,对于因输尿管绞痛到急诊科就诊的患者,非增强螺旋计算机断层扫描必须是首选方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/746e11ea313b/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/5fe7ecec8101/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/692c9318c27d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/48fd2552a55c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/f7985ee4c93d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/6c1ed02a901c/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/746e11ea313b/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/5fe7ecec8101/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/692c9318c27d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/48fd2552a55c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/f7985ee4c93d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/6c1ed02a901c/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/399a/9875159/746e11ea313b/gr6.jpg

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本文引用的文献

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J Pediatr Urol. 2021 Aug;17(4):475.e1-475.e6. doi: 10.1016/j.jpurol.2021.03.026. Epub 2021 Mar 30.
2
Protocol analysis of dual-energy CT for optimization of kidney stone detection in virtual non-contrast reconstructions.双能 CT 协议分析优化虚拟非增强重建中肾结石检测。
Eur Radiol. 2020 Aug;30(8):4295-4305. doi: 10.1007/s00330-020-06806-9. Epub 2020 Apr 3.
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Kidney and Ureteral Stones.肾和输尿管结石
Emerg Med Clin North Am. 2019 Nov;37(4):637-648. doi: 10.1016/j.emc.2019.07.004. Epub 2019 Aug 19.
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Imaging in Suspected Renal Colic: Systematic Review of the Literature and Multispecialty Consensus.疑似肾绞痛的影像学检查:文献系统评价和多学科共识。
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Pictorial review: Renal ultrasound.图片综述:肾脏超声
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Retrospective comparison of measured stone size and posterior acoustic shadow width in clinical ultrasound images.临床超声图像中测量结石大小与后向声影宽度的回顾性比较。
World J Urol. 2018 May;36(5):727-732. doi: 10.1007/s00345-017-2156-8. Epub 2017 Dec 14.
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Twinkle, twinkle little stone: an artifact improves the ultrasound performance!一闪一闪小结石:一种伪像改善了超声表现!
Med Ultrason. 2017 Jun 17;19(3):272-275. doi: 10.11152/mu-984.
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Ultrasound Use in Urinary Stones: Adapting Old Technology for a Modern-Day Disease.超声在尿路结石中的应用:使旧技术适应现代疾病
J Endourol. 2017 Apr;31(S1):S89-S94. doi: 10.1089/end.2016.0584. Epub 2016 Nov 3.
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