Zahed Maryam, Ranjbar Mohammad Ali, Azad Azita
Oral and Dental Disease Research Center, Department of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Biomed Res Int. 2020 Dec 26;2020:8835824. doi: 10.1155/2020/8835824. eCollection 2020.
Oro-dental diseases are prevalent in chronic liver failure (CLF) patients. The aim of this study was to evaluate the quality of life associated with oral health in candidates for liver transplant surgery.
The demographic information of 105 end-stage liver cirrhotic patients was collected. All patients were ordered a panoramic view for pretransplant dental evaluation. The DMFT (decayed-missing-filled tooth) index was calculated for dental examination. The model for end-stage liver disease (MELD) was used for the severity of liver disease. The OHIP-14 (Oral Health Impact Profile) questionnaire and GOHAI (Geriatric Oral Health Assessment Index) questionnaire were applied to evaluate the impact of oral disease on the quality of life.
A total of 79 patients thoroughly completed the questionnaires; 79.7% were male, 32.9% were over 50, and 25.3% were less than 30 years old. Further, 12.7% smoked, 2.5% were illiterate, 64.6% had not finished school, and 10.1% had university degrees. Almost half of the cirrhotic patients were suffering from the disease for more than 3 years. Most complaints reported by the patients as "very often" were becoming self-conscious (13.9%) and being uncomfortable when eating any foods (13.9%) followed by feeling tense (12.8%). There was no significant difference between gender, smoking, age, and MELD score based on quality of life (OHIP and GOHAI) ( > 0.05). The level of education ( = 0.020), duration of disease ( = 0.017), and DMFT index ( = 0.039) had a significant impact on oral health-related quality of life in CLF patients. An inverse relationship was seen between the DMFT index and the quality of life.
Oral health has a high impact on the quality of life of cirrhotic patients. The psychological dimension of oral health is the most debilitating factor affecting the quality of life. This shows the importance of professional oral care, oral health, and self-care education in this group of patients.
口腔疾病在慢性肝衰竭（CLF）患者中普遍存在。本研究的目的是评估肝移植手术候选者中与口腔健康相关的生活质量。
收集了105例终末期肝硬化患者的人口统计学信息。所有患者均接受全景牙片检查以进行移植前的牙科评估。计算DMFT（龋失补牙）指数用于牙科检查。使用终末期肝病模型（MELD）评估肝病的严重程度。应用OHIP-14（口腔健康影响程度量表）问卷和GOHAI（老年口腔健康评估指数）问卷评估口腔疾病对生活质量的影响。
共有79例患者完整填写了问卷；其中79.7%为男性，32.9%年龄超过50岁，25.3%年龄小于30岁。此外，12.7%的患者吸烟，文盲占2.5%，64.6%未完成学业，10.1%拥有大学学位。几乎一半的肝硬化患者患病超过3年。患者报告“非常频繁”出现的大多数不适症状依次为变得自觉（13.9%）、进食任何食物时感到不适（13.9%），其次是感到紧张（12.8%）。基于生活质量（OHIP和GOHAI），性别、吸烟、年龄和MELD评分之间无显著差异（P>0.05）。教育程度（P = 0.020）、病程（P = 0.017）和DMFT指数（P = 0.039）对CLF患者口腔健康相关生活质量有显著影响。DMFT指数与生活质量呈负相关。
口腔健康对肝硬化患者的生活质量有很大影响。口腔健康的心理维度是影响生活质量的最具削弱作用的因素。这表明了专业口腔护理、口腔健康和自我护理教育在这类患者中的重要性。
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