Rice Virginia Hill, Heath Laura, Livingstone-Banks Jonathan, Hartmann-Boyce Jamie
College of Nursing, Wayne State University, 5557 Cass Avenue, Detroit, Michigan, USA, 48202.
Cochrane Database Syst Rev. 2017 Dec 15;12(12):CD001188. doi: 10.1002/14651858.CD001188.pub5.
Healthcare professionals, including nurses, frequently advise people to improve their health by stopping smoking. Such advice may be brief, or part of more intensive interventions.
To determine the effectiveness of nursing-delivered smoking cessation interventions in adults. To establish whether nursing-delivered smoking cessation interventions are more effective than no intervention; are more effective if the intervention is more intensive; differ in effectiveness with health state and setting of the participants; are more effective if they include follow-ups; are more effective if they include aids that demonstrate the pathophysiological effect of smoking.
We searched the Cochrane Tobacco Addiction Group Specialized Register and CINAHL in January 2017.
Randomized trials of smoking cessation interventions delivered by nurses or health visitors with follow-up of at least six months.
Two review authors extracted data independently. The main outcome measure was abstinence from smoking after at least six months of follow-up. We used the most rigorous definition of abstinence for each trial, and biochemically-validated rates if available. Where statistically and clinically appropriate, we pooled studies using a Mantel-Haenszel fixed-effect model and reported the outcome as a risk ratio (RR) with a 95% confidence interval (CI).
Fifty-eight studies met the inclusion criteria, nine of which are new for this update. Pooling 44 studies (over 20,000 participants) comparing a nursing intervention to a control or to usual care, we found the intervention increased the likelihood of quitting (RR 1.29, 95% CI 1.21 to 1.38); however, statistical heterogeneity was moderate (I = 50%) and not explained by subgroup analysis. Because of this, we judged the quality of evidence to be moderate. Despite most studies being at unclear risk of bias in at least one domain, we did not downgrade the quality of evidence further, as restricting the main analysis to only those studies at low risk of bias did not significantly alter the effect estimate. Subgroup analyses found no evidence that high-intensity interventions, interventions with additional follow-up or interventions including aids that demonstrate the pathophysiological effect of smoking are more effective than lower intensity interventions, or interventions without additional follow-up or aids. There was no evidence that the effect of support differed by patient group or across healthcare settings.
AUTHORS' CONCLUSIONS: There is moderate quality evidence that behavioural support to motivate and sustain smoking cessation delivered by nurses can lead to a modest increase in the number of people who achieve prolonged abstinence. There is insufficient evidence to assess whether more intensive interventions, those incorporating additional follow-up, or those incorporating pathophysiological feedback are more effective than one-off support. There was no evidence that the effect of support differed by patient group or across healthcare settings.
包括护士在内的医疗保健专业人员经常建议人们通过戒烟来改善健康状况。此类建议可能很简短,或者是更密集干预措施的一部分。
确定护士提供的戒烟干预措施对成年人的有效性。确定护士提供的戒烟干预措施是否比不进行干预更有效;干预措施更密集时是否更有效;其有效性是否因参与者的健康状况和环境而异;包含随访时是否更有效;包含展示吸烟病理生理效应的辅助手段时是否更有效。
我们于2017年1月检索了Cochrane烟草成瘾小组专业注册库和护理学与健康领域数据库。
由护士或健康访视员提供的戒烟干预措施的随机试验,随访时间至少为六个月。
两名综述作者独立提取数据。主要结局指标是随访至少六个月后的戒烟情况。我们对每个试验采用了最严格的戒烟定义,如有可用数据则采用经生化验证的戒烟率。在统计学和临床适用的情况下,我们使用Mantel-Haenszel固定效应模型汇总研究,并将结局报告为风险比(RR)及95%置信区间(CI)。
58项研究符合纳入标准,其中9项是本次更新新增的。汇总44项研究(超过20000名参与者),这些研究将护理干预与对照或常规护理进行比较,我们发现干预措施增加了戒烟的可能性(RR 1.29,95%CI 1.21至1.38);然而,统计异质性为中度(I² = 50%),且未通过亚组分析得到解释。因此,我们判断证据质量为中等。尽管大多数研究在至少一个领域存在偏倚风险不明确的情况,但我们并未进一步降低证据质量,因为将主要分析仅限于那些偏倚风险较低的研究并未显著改变效应估计值。亚组分析未发现证据表明高强度干预、有额外随访的干预或包含展示吸烟病理生理效应辅助手段的干预比低强度干预、无额外随访或辅助手段的干预更有效。没有证据表明支持效果因患者群体或医疗环境而异。
有中等质量的证据表明,护士提供的激励和维持戒烟的行为支持可使实现长期戒烟的人数适度增加。没有足够的证据来评估更密集的干预措施、包含额外随访的干预措施或包含病理生理反馈的干预措施是否比一次性支持更有效。没有证据表明支持效果因患者群体或医疗环境而异。