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肥胖症的外科治疗

Surgical management of obesity.

作者信息

Torres-Landa Samuel, Kannan Umashankkar, Guajardo Isabella, Pickett-Blakely Octavia E, Dempsey Daniel T, Williams Noel N, Dumon Kristoffel R

机构信息

Department of Surgery, Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Department of Surgery, Bronx-Lebanon Hospital Center, New York, NY, USA.

出版信息

Minerva Chir. 2018 Feb;73(1):41-54. doi: 10.23736/S0026-4733.17.07588-5. Epub 2017 Dec 14.

Abstract

Obesity is a spreading epidemic associated with significant morbidity and mortality with a prevalence of over 36% worldwide. In the face of a growing epidemic, increasing medical costs, and the disappointing limitations of medical and lifestyle modification bariatric surgery was found to consistently lead to significant weight loss and improvement in obesity-associated comorbidities when compared to non-surgical interventions. Bariatric procedures fall within three basic categories: restrictive procedures, malabsorptive procedures, and procedures that combine both restrictive and malabsorptive mechanisms. Four major procedures are currently performed (most often laparoscopically): Roux-en-Y gastric bypass, biliopancreatic diversion with duodenal switch, adjustable gastric banding, and sleeve gastrectomy. Although the laparoscopic Roux-en-Y gastric bypass was the most frequently performed bariatric procedure, the laparoscopic sleeve gastrectomy has since become the most popular. Bariatric surgery currently has similar mortality rates to standard general surgical operations. Morevoer, bariatric surgery reduces mortality by the improvement and remission of obesity-related comorbidities. Newer minimally-invasive weight loss procedures and endoscopic methods continue to evolve as we expand our understanding of the intricacies of obesity and the effects of currently available surgical treatments.

摘要

肥胖是一种正在蔓延的流行病,与显著的发病率和死亡率相关,全球患病率超过36%。面对日益蔓延的疫情、不断增加的医疗成本以及医学和生活方式改变的令人失望的局限性,与非手术干预相比,减肥手术被发现始终能导致显著的体重减轻和肥胖相关合并症的改善。减肥手术可分为三大类:限制性手术、吸收不良性手术以及结合了限制性和吸收不良性机制的手术。目前主要进行四种手术(大多数通过腹腔镜进行):Roux-en-Y胃旁路术、胆胰转流十二指肠转位术、可调节胃束带术和袖状胃切除术。尽管腹腔镜Roux-en-Y胃旁路术是最常进行的减肥手术,但腹腔镜袖状胃切除术后来成为了最受欢迎的手术。目前减肥手术的死亡率与标准普通外科手术相似。此外,减肥手术通过改善和缓解肥胖相关合并症来降低死亡率。随着我们对肥胖的复杂性以及现有手术治疗效果的理解不断加深,更新的微创减肥手术和内镜方法也在不断发展。

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