寨卡病毒可通过埃及伊蚊在人群中进行性传播。
Zika virus can be venereally transmitted between Aedes aegypti mosquitoes.
机构信息
Laboratório de Mosquitos Transmissores de Hematozoários, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
Laboratório de Biologia Molecular de Flavivírus, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brazil.
出版信息
Parasit Vectors. 2017 Dec 15;10(1):605. doi: 10.1186/s13071-017-2543-4.
Abstract
BACKGROUND
Alternative transmission routes have been described for Zika virus (ZIKV). Here, we assessed for the first time the venereal transmission of ZIKV between Aedes aegypti under laboratory conditions.
RESULTS
Orally-infected mosquito females were able to transmit the virus to males venereally, and males inoculated intrathoracically were capable of infecting females during mating. The genome of venereally-transmitted virus recovered from males was identical to that of ZIKV ingested by mated females.
CONCLUSION
We conclude that venereal transmission between Aedes mosquitoes might contribute to Zika virus maintenance in nature.
摘要
背景
寨卡病毒（ZIKV）存在多种可能的传播途径。本研究首次在实验室条件下评估了埃及伊蚊（Aedes aegypti）之间的性传播。
结果
经口感染的雌性蚊子能够通过性途径将病毒传播给雄性蚊子，而经胸部接种的雄性蚊子在交配时能够感染雌性蚊子。从雄性蚊子中恢复的性传播病毒的基因组与交配雌性蚊子摄入的 ZIKV 相同。
结论
我们的结论是，埃及伊蚊之间的性传播可能有助于寨卡病毒在自然界中的维持。
相似文献
1
Zika virus can be venereally transmitted between Aedes aegypti mosquitoes.寨卡病毒可通过埃及伊蚊在人群中进行性传播。
Parasit Vectors. 2017 Dec 15;10(1):605. doi: 10.1186/s13071-017-2543-4.
2
Zika virus transmission to mouse ear by mosquito bite: a laboratory model that replicates the natural transmission process.寨卡病毒通过蚊虫叮咬传播至小鼠耳部：一种模拟自然传播过程的实验室模型。
Parasit Vectors. 2017 Jul 20;10(1):346. doi: 10.1186/s13071-017-2286-2.
3
Evidence for infection but not transmission of Zika virus by Aedes albopictus (Diptera: Culicidae) from Spain.证据表明，西班牙白纹伊蚊（双翅目：蚊科）可感染寨卡病毒但不会传播该病毒。
Parasit Vectors. 2019 May 3;12(1):204. doi: 10.1186/s13071-019-3467-y.
4
Vector competence of Virginia mosquitoes for Zika and Cache Valley viruses.弗吉尼亚州蚊虫对寨卡病毒和卡什谷病毒的媒介效能。
Parasit Vectors. 2020 Apr 10;13(1):188. doi: 10.1186/s13071-020-04042-0.
5
Surveillance of Zika virus in field-caught Aedes aegypti and Aedes albopictus suggests important role of male mosquitoes in viral populations maintenance in Medellín, Colombia.野外捕获的埃及伊蚊和白纹伊蚊中寨卡病毒的监测表明，雄性蚊子在哥伦比亚麦德林的病毒种群维持中发挥了重要作用。
Infect Genet Evol. 2020 Nov;85:104434. doi: 10.1016/j.meegid.2020.104434. Epub 2020 Jun 21.
6
Microbial Composition in Larval Water Enhances Aedes aegypti Development but Reduces Transmissibility of Zika Virus.幼虫水中的微生物组成可促进埃及伊蚊的发育，但降低寨卡病毒的传播能力。
mSphere. 2021 Dec 22;6(6):e0068721. doi: 10.1128/msphere.00687-21. Epub 2021 Dec 8.
7
Evidence of vertical transmission of Zika virus in field-collected eggs of Aedes aegypti in the Brazilian Amazon.在巴西亚马逊地区采集的埃及伊蚊卵中发现寨卡病毒的垂直传播证据。
PLoS Negl Trop Dis. 2018 Jul 16;12(7):e0006594. doi: 10.1371/journal.pntd.0006594. eCollection 2018 Jul.
8
First evidence of Zika virus venereal transmission in Aedes aegypti mosquitoes.寨卡病毒在埃及伊蚊中通过性传播的首个证据。
Mem Inst Oswaldo Cruz. 2018 Jan;113(1):56-61. doi: 10.1590/0074-02760170329. Epub 2017 Nov 27.
9
Zika virus outbreak in the Pacific: Vector competence of regional vectors.太平洋地区的 Zika 病毒爆发：区域传播媒介的媒介效能。
PLoS Negl Trop Dis. 2018 Jul 17;12(7):e0006637. doi: 10.1371/journal.pntd.0006637. eCollection 2018 Jul.
10
Restriction of Zika virus infection and transmission in Aedes aegypti mediated by an insect-specific flavivirus.通过一种昆虫特异性黄病毒限制埃及伊蚊中的寨卡病毒感染和传播。
Emerg Microbes Infect. 2018 Nov 15;7(1):181. doi: 10.1038/s41426-018-0180-4.
引用本文的文献
1
The Frontier of Entomo-Virology: Applications and Tools for Virus and Vector Surveillance.昆虫病毒学前沿：病毒与媒介监测的应用及工具
Pathogens. 2025 Jul 15;14(7):699. doi: 10.3390/pathogens14070699.
2
Eggs-posed: revision of Schistosoma mansoni venom allergen-like proteins unveils new genes and offers new insights into egg-host interactions.卵相关：曼氏血吸虫毒液过敏原样蛋白的修订揭示新基因并为卵与宿主相互作用提供新见解
BMC Genomics. 2025 Feb 24;26(1):189. doi: 10.1186/s12864-025-11369-4.
3
Zika virus transmission in Aedes aegypti: A systematic study on the ability of mosquitoes to transmit the virus horizontally and vertically.寨卡病毒在埃及伊蚊中的传播：关于蚊子水平和垂直传播该病毒能力的系统研究。
Virol Sin. 2025 Apr;40(2):192-205. doi: 10.1016/j.virs.2025.02.001. Epub 2025 Feb 11.
4
In Vitro Assessment of Metarhizium Anisopliae Pathogenicity Against Aedes Aegypti Life Stages.体外评估玫烟色拟青霉对埃及伊蚊各生活阶段的致病性。
Neotrop Entomol. 2024 Dec;53(6):1260-1270. doi: 10.1007/s13744-024-01209-7. Epub 2024 Oct 9.
5
Vector competence of Culex quinquefasciatus for Tembusu virus and viral factors for virus transmission by mosquitoes.致倦库蚊对 Tembusu 病毒的媒介效能及病毒通过蚊虫传播的相关因素。
Vet Res. 2024 Sep 18;55(1):109. doi: 10.1186/s13567-024-01361-3.
6
High prevalence of Zika virus infection in populations of Aedes aegypti from South-western Ecuador.西南厄瓜多尔埃及伊蚊种群中寨卡病毒感染的高流行率。
PLoS Negl Trop Dis. 2024 Jan 18;18(1):e0011908. doi: 10.1371/journal.pntd.0011908. eCollection 2024 Jan.
7
Persistence of Tembusu Virus in in Yunnan Province, China.中国云南省坦布苏病毒的持续性
Pathogens. 2023 Mar 21;12(3):490. doi: 10.3390/pathogens12030490.
8
Arboviruses and symbiotic viruses cooperatively hijack insect sperm-specific proteins for paternal transmission.虫媒病毒和共生病毒协同劫持昆虫精子特异性蛋白以进行父本传递。
Nat Commun. 2023 Mar 9;14(1):1289. doi: 10.1038/s41467-023-36993-0.
9
Modeling the spread of the Zika virus by sexual and mosquito transmission.通过性传播和蚊虫传播建模寨卡病毒的传播。
PLoS One. 2022 Dec 30;17(12):e0270127. doi: 10.1371/journal.pone.0270127. eCollection 2022.
10
Evidence of Spreading Zika Virus Infection Caused by Males of Different Species.证据表明，不同物种的雄性可传播寨卡病毒感染。
Viruses. 2022 Sep 15;14(9):2047. doi: 10.3390/v14092047.
本文引用的文献
1
Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network.美洲地区的寨卡疫情第二年：我们学到了什么？仍存在哪些差距？全球病毒网络的一份报告
Antiviral Res. 2017 Aug;144:223-246. doi: 10.1016/j.antiviral.2017.06.001. Epub 2017 Jun 6.
2
Zika puzzle in Brazil: peculiar conditions of viral introduction and dissemination - A Review.巴西的寨卡谜题：病毒引入与传播的特殊情况——综述
Mem Inst Oswaldo Cruz. 2017 May;112(5):319-327. doi: 10.1590/0074-02760160510. Epub 2017 Apr 6.
3
Vertical Transmission of Zika Virus by Aedes aegypti and Ae. albopictus Mosquitoes.埃及伊蚊和白纹伊蚊对寨卡病毒的垂直传播
Emerg Infect Dis. 2017 May;23(5):880-882. doi: 10.3201/eid2305.162041. Epub 2017 May 15.
4
First detection of natural infection of Aedes aegypti with Zika virus in Brazil and throughout South America.在巴西乃至整个南美洲首次检测到埃及伊蚊自然感染寨卡病毒。
Mem Inst Oswaldo Cruz. 2016 Oct;111(10):655-658. doi: 10.1590/0074-02760160332. Epub 2016 Oct 3.
5
Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil.巴西累西腓的 Zika 病毒全基因组序列及其 sfRNA 干扰素拮抗活性。
PLoS Negl Trop Dis. 2016 Oct 5;10(10):e0005048. doi: 10.1371/journal.pntd.0005048. eCollection 2016 Oct.
6
Mapping the global geographic potential of Zika virus spread.绘制寨卡病毒传播的全球地理潜在范围。
Mem Inst Oswaldo Cruz. 2016 Sep;111(9):559-60. doi: 10.1590/0074-02760160149.
7
Culex quinquefasciatus from Rio de Janeiro Is Not Competent to Transmit the Local Zika Virus.里约热内卢致倦库蚊不适宜传播当地的 Zika 病毒。
PLoS Negl Trop Dis. 2016 Sep 6;10(9):e0004993. doi: 10.1371/journal.pntd.0004993. eCollection 2016 Sep.
8
Infection dynamics in a traveller with persistent shedding of Zika virus RNA in semen for six months after returning from Haiti to Italy, January 2016.2016年1月，一名从海地返回意大利的旅行者精液中持续六个月检测出寨卡病毒RNA的感染动态。
Euro Surveill. 2016 Aug 11;21(32). doi: 10.2807/1560-7917.ES.2016.21.32.30316.
9
Travel-associated and autochthonous Zika virus infection in mainland France, 1 January to 15 July 2016.2016年1月1日至7月15日法国本土与旅行相关及本地传播的寨卡病毒感染情况
Euro Surveill. 2016 Aug 11;21(32). doi: 10.2807/1560-7917.ES.2016.21.32.30315.
10
Isolation of Infective Zika Virus from Urine and Saliva of Patients in Brazil.从巴西患者的尿液和唾液中分离出感染性寨卡病毒。
PLoS Negl Trop Dis. 2016 Jun 24;10(6):e0004816. doi: 10.1371/journal.pntd.0004816. eCollection 2016 Jun.
Zotero 插件