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鳞状细胞癌相关抗原在银屑病和泛发性湿疹中的意义。初步报告。

Significance of squamous cell carcinoma-related antigen in psoriasis and generalized eczema. Preliminary report.

作者信息

Numahara T, Nakashima K, Yamamoto S, Nishimoto M

机构信息

Department of Dermatology, Kagawa Medical School, Japan.

出版信息

Dermatologica. 1989;178(2):73-4. doi: 10.1159/000248395.

Abstract

The serum levels of squamous cell carcinoma-related antigen (SCC-RAG) were assayed in 15 cases of benign dermatoses. The SCC-RAG titers (2.0 ng/ml as the cutoff value) were elevated in all cases of wide-spreading psoriasis (7 cases, 2.4-96.1 ng/ml) and all cases of generalized eczema (3 cases, 11.2-33.6 ng/ml). The serum SCC-RAG levels correlated with clinical course of these dermatoses. Therefore, the increase in this cancer-related antigen is not specific for SCC but may also occur in a wide range of dermatoses.

摘要

对15例良性皮肤病患者检测了血清鳞状细胞癌相关抗原(SCC-RAG)水平。所有泛发性银屑病患者(7例,2.4 - 96.1 ng/ml)和所有泛发性湿疹患者(3例,11.2 - 33.6 ng/ml)的SCC-RAG滴度(以2.0 ng/ml为临界值)均升高。血清SCC-RAG水平与这些皮肤病的临床病程相关。因此,这种癌症相关抗原的升高并非鳞状细胞癌所特有,也可能发生在多种皮肤病中。

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