Center for Plant Aging Research, Institute for Basic Science (IBS), Daegu, Republic of Korea.
Agricultural Genomics Institute, Chinese Academy of Agricultural Sciences, Shenzhen, China.
J Exp Bot. 2018 Feb 12;69(4):801-810. doi: 10.1093/jxb/erx401.
Leaf senescence is not only genetically programmed but also induced by exogenous stress to ensure completion of the plant life cycle, successful reproduction and environmental adaptability. Genetic reprogramming is a major aspect of leaf senescence, and the senescence signaling that follows is controlled by a complex regulatory network. Recent studies suggest that the activity of transcription factors together with epigenetic mechanisms ensures the robustness of this network, with the latter including chromatin remodeling, DNA modification, and RNA-mediated control of transcription factors and other senescence-associated genes. In this review, we provide an overview of the relevant epigenetic mechanisms and summarize recent findings of epigenetic regulators of plant leaf senescence involved in DNA methylation and histone modification along with the functions of small RNAs in this process.
叶片衰老不仅受到遗传程序的调控，也受到外源胁迫的诱导，以确保植物生命周期的完成、成功繁殖和环境适应性。遗传重编程是叶片衰老的一个主要方面，随后的衰老信号受一个复杂的调控网络控制。最近的研究表明，转录因子的活性以及表观遗传机制确保了这个网络的稳健性，后者包括染色质重塑、DNA 修饰以及 RNA 对转录因子和其他衰老相关基因的转录调控。在这篇综述中，我们概述了相关的表观遗传机制，并总结了近年来涉及 DNA 甲基化和组蛋白修饰的植物叶片衰老的表观遗传调控因子以及小 RNA 在这个过程中的功能的发现。
