Ishigooka H, Hirata A, Kitaoka T, Ueno S
Department of Ophthalmology, Faculty of Medicine, Kyoto University, Japan.
Invest Ophthalmol Vis Sci. 1989 Mar;30(3):509-20.
The cytochemical localization of G6Pase activity, which is specific to the endoplasmic reticulum (ER) of Müller cells, was studied after argon laser photocoagulation in the guinea pig retina. After argon laser radiation, Müller cells exhibited enlargement of the cytoplasm, an increase of reactive ER and the nuclei, dislocation of the nuclei and diagonal stretching of the cytoplasm. However, cell attachment between Müller cells and the proliferated pigment epithelial cells or Bruch's membrane differed with the degree of retinal coagulation. This histo- and cytochemical method may be useful for examining Müller cells under various pathological conditions.
在豚鼠视网膜氩激光光凝后，研究了葡萄糖-6-磷酸酶（G6Pase）活性的细胞化学定位，该酶活性是 Müller 细胞内质网（ER）所特有的。氩激光照射后，Müller 细胞表现出细胞质增大、反应性内质网和细胞核增多、细胞核移位以及细胞质对角伸展。然而，Müller 细胞与增殖的色素上皮细胞或 Bruch 膜之间的细胞附着情况因视网膜凝固程度而异。这种组织化学和细胞化学方法可能有助于在各种病理条件下检查 Müller 细胞。
