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ADHD 的早期预测指标:来自前瞻性出生队列的证据。

Early Predictors of ADHD: Evidence from a Prospective Birth Cohort.

机构信息

Oslo University Hospital, Norway.

Norwegian Institute of Public Health, Oslo, Norway.

出版信息

J Atten Disord. 2020 Oct;24(12):1685-1692. doi: 10.1177/1087054717696765. Epub 2017 Mar 9.

DOI:10.1177/1087054717696765
PMID:29254401
Abstract

To identify preschool predictors of registered ADHD diagnoses and compare two ADHD rating scales, Child Behavior Checklist (CBCL) and Conners' Parent Rating Scale (CPRS-R:S). The Norwegian Mother and Child Cohort study (MoBa) is a prospective population-based cohort study. The sample were singletons whose mothers responded to MoBa questionnaires at child age 3 years ( = 57,986) and 5 years ( = 32,377). ADHD diagnoses were obtained from the Norwegian Patient Register. Predictors were child gender, development and symptoms, and maternal ADHD symptoms. We used Cox proportional hazard regression analyses. In all final models, ADHD symptoms at age 3 and 5 years predicted later ADHD: Age 3, CBCL: hazard ratio (HR) = 3.23 (CI [2.59, 4.02]); age 5, CBCL: HR = 10.30 (CI [7.44, 14.26]); and age 5 CPRS-R:S: HR = 5.92 (CI [4.95, 7.07]). The findings underline the importance of taking early parent-reported symptoms seriously. Both rating scales were useful for predicting ADHD.

摘要

为了确定学龄前儿童患多动症的预测因素,并比较两种多动症评定量表,即儿童行为检查表(CBCL)和康纳斯父母评定量表修订版(CPRS-R:S)。挪威母婴队列研究(MoBa)是一项前瞻性的基于人群的队列研究。该样本为单胎,其母亲在孩子 3 岁(=57986)和 5 岁(=32377)时回答了 MoBa 问卷。多动症的诊断是从挪威患者登记处获得的。预测因素包括儿童的性别、发育和症状以及母亲的多动症症状。我们使用 Cox 比例风险回归分析。在所有最终模型中,3 岁和 5 岁时的多动症症状均预测了以后的多动症:3 岁时,CBCL:危险比(HR)=3.23(CI [2.59, 4.02]);5 岁时,CBCL:HR=10.30(CI [7.44, 14.26]);5 岁时 CPRS-R:S:HR=5.92(CI [4.95, 7.07])。这些发现强调了认真对待早期父母报告的症状的重要性。两种评定量表都能很好地预测多动症。

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