密罗霉素C，一种来自疣孢漆斑菌的新型二萜类抗肿瘤抗生素。II. 物理化学性质及结构测定
Myrocin C, a new diterpene antitumor antibiotic from Myrothecium verrucaria. II. Physico-chemical properties and structure determination.
作者信息
Hsu Y H, Hirota A, Shima S, Nakagawa M, Adachi T, Nozaki H, Nakayama M
机构信息
Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture, Japan.
出版信息
J Antibiot (Tokyo). 1989 Feb;42(2):223-9. doi: 10.7164/antibiotics.42.223.
PMID:2925513
Abstract
The structure of a new antitumor antibiotic, myrocin C, from a strain of Myrothecium verrucaria was characterized as a pentacyclic pimarane diterpene composed of a gamma-lactol group and a unique cyclopropane ring on the basis of its physico-chemical properties and spectroscopic data as well as a single-crystal X-ray diffraction analysis of its monoacetyl derivative.
摘要
从疣孢漆斑菌菌株中分离出的一种新型抗肿瘤抗生素——漆斑霉素C，基于其物理化学性质、光谱数据以及对其单乙酰衍生物的单晶X射线衍射分析，其结构被鉴定为一种由γ-内酯基团和独特环丙烷环组成的五环海松烷二萜。
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