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两例李氏杆菌性菱形脑炎

Two cases of listeria rhombencephalitis.

作者信息

Mansbridge Christopher Thomas, Grecu Irina, Li Voon Chong Jimmy Sw, Vandervelde Clive, Saeed Kordo

机构信息

Royal Hampshire County Hospital, Hampshire Hospitals NHS Foundation Trust, Romsey Road, Winchester, Hampshire, SO22 5DG, United Kingdom.

School of Medicine, University of Southampton, Southampton, Hampshire, SO16 6YD, United Kingdom.

出版信息

IDCases. 2017 Dec 5;11:22-25. doi: 10.1016/j.idcr.2017.12.002. eCollection 2018.

Abstract

Listeria rhombencephalitis (LRE) is a rare encephalitis of the hindbrain that can present with a variety of neurological symptoms. It is a diagnostic challenge, but prompt antimicrobial therapy is important to prevent high rates of mortality and morbidity. We report two cases of LRE, with several contrasting clinical features and different disease courses. Despite being rare, it is important to consider listeria in patients with possible meningoencephalitis, even if cultures are negative. Empirical treatment of meningoencephalitis should provide coverage for listeria, especially if the patient is at risk of listeriosis or there is a potential history of listeria exposure.

摘要

菱形脑炎(LRE)是一种罕见的后脑脑炎,可表现出多种神经症状。它是一项诊断难题,但及时进行抗菌治疗对于预防高死亡率和高发病率至关重要。我们报告了两例LRE病例,具有一些截然不同的临床特征和不同的病程。尽管罕见,但对于可能患有脑膜脑炎的患者,即使培养结果为阴性,考虑李斯特菌感染也很重要。对脑膜脑炎进行经验性治疗时应涵盖李斯特菌,特别是如果患者有李斯特菌病风险或有潜在的李斯特菌接触史。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82f4/5726744/836616c59589/gr1.jpg

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