Prince Jonathan D, Oyo Adashima, Mora Olivia, Wyka Katarzyna, Schonebaum Andrew D
J Nerv Ment Dis. 2018 Feb;206(2):136-141. doi: 10.1097/NMD.0000000000000768.
Although studies show that loneliness increases risk of illness and hastens death, it is poorly understood among persons with severe mental illness (SMI). Using data on 150 people with SMI, we used logistic regression to predict (1) loneliness from sociodemographic and clinical characteristics, and (2) psychiatric hospitalization from presence of loneliness. We also examined mediating effects. Study participants who were most willing to ask for help were 70% less likely (odds ratio [OR], 0.30; confidence interval [CI], 0.09-0.99; p < 0.05) to be lonely than those who were least willing, and participants with high levels of internalized stigma were 9.25 times as likely (CI, 9.25; OR, 2.29-37.32; p < 0.01) as other participants to be lonely. Participants who were most lonely were 2.69 times (CI, 1.03-7.04, p < 0.05) as likely to be placed in psychiatric hospitals as those who were less lonely. Loneliness mediates the association between internalized stigma and psychiatric hospitalization (OR, 1.30; CI, 1.04-1.73). Findings can be used to help prevent inpatient stay.
尽管研究表明孤独会增加患病风险并加速死亡，但严重精神疾病（SMI）患者对其了解甚少。我们利用150名严重精神疾病患者的数据，通过逻辑回归来预测：（1）从社会人口统计学和临床特征来判断孤独感；（2）根据孤独感的存在情况来预测精神科住院治疗情况。我们还研究了中介效应。最愿意寻求帮助的研究参与者感到孤独的可能性比最不愿意寻求帮助的参与者低70%（优势比[OR]，0.30；置信区间[CI]，0.09 - 0.99；p < 0.05），内化耻辱感程度高的参与者感到孤独的可能性是其他参与者的9.25倍（CI，9.25；OR，2.29 - 37.32；p < 0.01）。孤独感最强的参与者被送入精神病院的可能性是孤独感较弱参与者的2.69倍（CI，1.03 - 7.04，p < 0.05）。孤独感介导了内化耻辱感与精神科住院治疗之间的关联（OR，1.30；CI，1.04 - 1.73）。研究结果可用于帮助预防住院治疗。
