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采用衣原体科引物的呼吸道多重聚合酶链反应检测法揭示沙眼衣原体和鹦鹉热衣原体的诊断不足。

Underdiagnosis of Chlamydia trachomatis and Chlamydia psittaci revealed by introduction of respiratory multiplex PCR assay with Chlamydiaceae family primers.

作者信息

Rane Vinita, Khailin Kong, Williams Jackie, Francis Michelle, Kotsanas Despina, Korman Tony M, Graham Maryza

机构信息

Monash Infectious Diseases, Monash University, Monash Health, Clayton, Australia.

Monash Infectious Diseases, Monash University, Monash Health, Clayton, Australia.

出版信息

Diagn Microbiol Infect Dis. 2018 Mar;90(3):163-166. doi: 10.1016/j.diagmicrobio.2017.11.013. Epub 2017 Nov 26.

DOI:10.1016/j.diagmicrobio.2017.11.013
PMID:29258707
Abstract

We describe unanticipated detection of respiratory infection with Chlamydia trachomatis and Chlamydia psittaci after introduction of respiratory multiplex polymerase chain reaction assay that includes Chlamydiaceae family primers. We detected cases of pediatric C. trachomatis and of adult C. psittaci infection in patients with previously unrecognized risk factors. Directed testing for C. trachomatis and C. psittaci based on clinical features and risk factors alone is likely to miss the majority of infected cases.

摘要

我们描述了在引入包含衣原体科引物的呼吸道多重聚合酶链反应检测方法后，意外检测到沙眼衣原体和鹦鹉热衣原体引起的呼吸道感染。我们在具有先前未被识别的危险因素的患者中检测到小儿沙眼衣原体感染病例和成人鹦鹉热衣原体感染病例。仅基于临床特征和危险因素对沙眼衣原体和鹦鹉热衣原体进行针对性检测很可能会漏诊大多数感染病例。

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