Sladkova I A, Chinenova T A, Lomovskaia N D, Mkrtumian N M
Genetika. 1979 Nov;15(11):1953-62.
Actinophage phi C31 of Streptomyces coelicolor A3 (2) and two novel temperate actinophages phi C43 and phi C62 isolated from strains of blue actinomycetes group are homoimmune, serologically and functionally related. DNA molecules of phages phi C31, phi C43 and phi C62 have cohesive ends; sizes of DNAs of these phages and some mutants have been determined. The extent of homology between the DNAs of three phages is 93-96% as shown by heteroduplex analysis. The regions of non-homology are of a deletion-insertion type and of approximately 1500 base pairs in the length. Location of deletions in DNAs of mutant phages phi C31 vd and phi C31 c5 has been shown. Structural modifications in phage dnas have been found only to occur in the right part of molecules. Heteroduplex maps have been constructed for all phages studied.
天蓝色链霉菌A3(2)的肌动噬菌体φC31以及从蓝色放线菌组菌株中分离出的两种新型温和肌动噬菌体φC43和φC62是同免疫、血清学和功能相关的。噬菌体φC31、φC43和φC62的DNA分子具有粘性末端；已确定了这些噬菌体及其一些突变体的DNA大小。异源双链分析表明，三种噬菌体DNA之间的同源程度为93-96%。非同源区域为缺失-插入型，长度约为1500个碱基对。已显示出突变噬菌体φC31 vd和φC31 c5的DNA中缺失的位置。仅在分子的右侧发现噬菌体DNA的结构修饰。已为所有研究的噬菌体构建了异源双链图谱。
