Grether J K, Schulman J
California Birth Defects Monitoring Program, Department of Health Services, Emeryville 94608.
J Pediatr. 1989 Apr;114(4 Pt 1):561-7. doi: 10.1016/s0022-3476(89)80694-8.
We studied 2962 cases of sudden infant death syndrome (SIDS), derived from linked birth and death records, to specify further the descriptive epidemiologic data on recognized SIDS risk factors and to examine interrelationships among multiple risk factors and SIDS while controlling for the influence of birth weight (using logistic regression). The results generally confirmed those of other studies, with the exception of a higher incidence of SIDS among Chinese and Japanese babies and a lower incidence among Hispanic babies, all in comparison with white, non-Spanish (Anglo) infants. Median age at death was found to vary by birth weight, with very low birth weight babies being about 6 weeks older (postnatal age) than normal birth weight babies at time of death. The association of the risk factors with SIDS remained when birth weight data were statistically controlled; the association of these risk factors with SIDS cannot be explained by their relationship to birth weight. An interaction was found between race and maternal age and between multiparity and type of hospital of birth. There was no interaction between birth weight and the other risk factors.
我们研究了2962例源于出生与死亡记录关联的婴儿猝死综合征（SIDS）病例，以进一步明确已确认的SIDS风险因素的描述性流行病学数据，并在控制出生体重影响的情况下（使用逻辑回归），研究多个风险因素与SIDS之间的相互关系。结果总体上证实了其他研究的结果，但与白人、非西班牙裔（盎格鲁）婴儿相比，中国和日本婴儿的SIDS发病率较高，西班牙裔婴儿的发病率较低。发现死亡时的中位年龄因出生体重而异，极低出生体重儿在死亡时的（出生后）年龄比正常出生体重儿大6周左右。在对出生体重数据进行统计学控制后，风险因素与SIDS之间的关联仍然存在；这些风险因素与SIDS之间的关联无法用它们与出生体重的关系来解释。发现种族与母亲年龄之间以及多胎妊娠与出生医院类型之间存在相互作用。出生体重与其他风险因素之间没有相互作用。
