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印度尼西亚东部成釉细胞瘤的流行病学、治疗及并发症:6年回顾性研究

The Epidemiology, treatment, and complication of ameloblastoma in East-Indonesia: 6 years retrospective study.

作者信息

Ruslin M, Hendra F-N, Vojdani A, Hardjosantoso D, Gazali M, Tajrin A, Wolff J, Forouzanfar T

机构信息

Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands, De Boelelaan 1117 1081 HV Amsterdam,

出版信息

Med Oral Patol Oral Cir Bucal. 2018 Jan 1;23(1):e54-e58. doi: 10.4317/medoral.22185.

DOI:10.4317/medoral.22185
PMID:29274152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5822540/
Abstract

BACKGROUND

Ameloblastoma is a neoplasm classified as a benign epithelial odontogenic tumor of the jaws, grow slowly and are locally invasive. The aim of the present study was to investigate the incidence, treatment, and complication of patients with ameloblastoma in East-Indonesia during six years retrospective study.

MATERIAL AND METHODS

This retrospective study included 84 patients who were diagnosed with ameloblastoma from 2011 to 2016. There were 56 patients with treatment data available. Data from each patient, including gender, age, histologic type, the size of the tumor, radiologic form, tumor location, type of treatment, and complication were reviewed and analyzed retrospectively.

RESULTS

Fourteen patients were diagnosed with unicystic ameloblastoma (25%), thirty two patients with multicystic follicular ameloblastoma (57%) and ten patients with an unspecified multicystic ameloblastoma (18%). A total of about 35 patients were treated conservatively (62.5%) and 21 patients were treated radically (37.5%). Swelling was present as a pre-operative complication in all 56 cases (100%). There were no complaints concerning speech.

CONCLUSIONS

The majority findings of the histologic type were multicystic ameloblastoma and their location were in the mandible. Most ameloblastoma were treated conservatively and reconstructions were made with only titanium plates and not bone graft.

摘要

背景

成釉细胞瘤是一种被归类为颌骨良性上皮性牙源性肿瘤的肿瘤,生长缓慢且具有局部侵袭性。本研究的目的是通过六年的回顾性研究,调查印度尼西亚东部成釉细胞瘤患者的发病率、治疗方法及并发症。

材料与方法

这项回顾性研究纳入了2011年至2016年期间被诊断为成釉细胞瘤的84例患者。其中有56例患者有治疗数据。对每位患者的数据进行回顾性审查和分析,包括性别、年龄、组织学类型、肿瘤大小、放射学形态、肿瘤位置、治疗类型及并发症。

结果

14例患者被诊断为单囊性成釉细胞瘤(25%),32例为多囊性滤泡状成釉细胞瘤(57%),10例为未明确的多囊性成釉细胞瘤(18%)。共有约35例患者接受了保守治疗(62.5%),21例患者接受了根治性治疗(37.5%)。在所有56例病例中(100%),肿胀是术前并发症。未出现与言语相关的问题。

结论

组织学类型的主要发现是多囊性成釉细胞瘤,其位置在下颌骨。大多数成釉细胞瘤接受了保守治疗,仅用钛板进行重建,未进行骨移植。

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