McKenna P, Willison J R, Phil B, Lowe D, Neil-Dwyer G
Department of Psychology, Brook Hospital, London, England.
Neurosurgery. 1989 Mar;24(3):361-7. doi: 10.1227/00006123-198903000-00009.
In this prospective study, 100 patients with subarachnoid haemorrhage (SAH) were assessed at discharge, 3 months, and 1 year using modern methods of neuropsychology to examine cognitive status and semistructured interviews to assess changes in personality and quality of life. A control group of 50 patients suffering myocardial infarction were also assessed at discharge and 1 year. Results of cognitive testing in the SAH group were unremarkable and compared well with the control group. Similarly, there was no evidence of a consequent reduction in the quality of life in the majority of the SAH patients. These results lead us to conclude that where the medical and surgical course of SAH is uncomplicated, patients recover with no permanent or significant reduction in their intellectual ability of life status. Possible reasons for the difference between these results and those of other studies are discussed.
在这项前瞻性研究中，采用现代神经心理学方法对100例蛛网膜下腔出血（SAH）患者在出院时、3个月和1年时进行评估，以检查认知状况，并通过半结构化访谈评估人格和生活质量的变化。还对50例心肌梗死患者的对照组在出院时和1年时进行了评估。SAH组的认知测试结果不显著，与对照组相比情况良好。同样，大多数SAH患者没有证据表明生活质量随之下降。这些结果使我们得出结论，在SAH的医疗和手术过程无并发症的情况下，患者康复后其智力或生活状况不会出现永久性或显著下降。文中还讨论了这些结果与其他研究结果存在差异的可能原因。
