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初产妇年龄、产次与健康相关生命质量的关系。

The relationships between timing of first childbirth, parity, and health-related quality of life.

机构信息

Center for International Health Research, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

出版信息

Qual Life Res. 2018 Apr;27(4):937-943. doi: 10.1007/s11136-017-1770-7. Epub 2017 Dec 26.

Abstract

PURPOSE

A few studies have investigated the relationship between age at first childbirth and health-related quality of life (HRQoL). This study examined the relationship between age at first childbirth and HRQoL and whether parity mediates this timing of the first childbirth-HRQoL relationship in women aged 50 years or above.

METHODS

The study population included 5146 parous women ≥ 50 years in the cross-sectional survey, the Korea National Health and Nutrition Examination Survey 2010-2012. HRQoL was evaluated by the EuroQol five-dimensional descriptive system. Participants were grouped according to quartiles of age at first childbirth (ranges: 13-21, 22-23, 24-25, and 26-44 years). This study used linear regression analysis to examine the relationship between age at first childbirth and HRQoL and on each dimension. Mediation analysis was used to examine the contribution of age at first childbirth to HRQoL and to each dimension.

RESULTS

This study found the increasing pattern of HRQoL across quartiles of age at first childbirth (P for trend = 0.030). Odds of problems in self-care and anxiety/depression dimensions significantly increased across the quartiles. Women with later age at first childbirth tended to have better HRQoL (B = 0.352, P = 0.003); parity significantly contributed to this relationship. Decreasing parity accounted for 33.5% of the relationship between late first childbirth and increased HRQoL. Early age at first childbirth significantly increased odds of the mobility problem through increasing parity.

CONCLUSIONS

Women of an early age at first childbirth tended to have lower HRQoL through giving more deliveries. Our findings suggest that more attention needs to be given to women with early pregnancy and more delivery to prevent impaired HRQoL.

摘要

目的

已有一些研究调查了初育年龄与健康相关生活质量(HRQoL)之间的关系。本研究检验了初育年龄与 HRQoL 之间的关系,以及初育年龄与 HRQoL 的关系是否通过生育次数来调节。

方法

本研究的研究人群包括参加 2010-2012 年韩国国家健康与营养调查的 5146 名 50 岁及以上的经产妇女。使用欧洲五维健康量表评价 HRQoL。参与者按初育年龄的四分位数分组(范围:13-21、22-23、24-25 和 26-44 岁)。本研究采用线性回归分析检验初育年龄与 HRQoL 及各维度之间的关系。采用中介分析检验初育年龄对 HRQoL 及各维度的贡献。

结果

本研究发现,HRQoL 随初育年龄的增加而呈上升趋势(趋势 P=0.030)。在自我护理和焦虑/抑郁维度上,各四分位数组间的问题发生率显著增加。初育年龄较晚的妇女 HRQoL 较好(B=0.352,P=0.003),生育次数对此关系有显著贡献。生育次数减少解释了晚初育与 HRQoL 改善之间 33.5%的关系。早初育通过增加生育次数显著增加了活动问题的可能性。

结论

早初育的妇女通过多次分娩,其 HRQoL 较低。本研究结果表明,需要更加关注早孕期和多次分娩的妇女,以预防 HRQoL 受损。

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