Ranganathan Murugan, Balaji M, Krishnaraj R, Narayanan Vivek, Thangavelu Annamalai
Department of Oral and Maxillofacial Surgery, Rajah Muthiah Dental College, Chidambaram, Tamil Nadu, India.
Department of Dental Surgery, Dhanalakshmi Srinivasan Medical College, Perambalur, Tamil Nadu, India.
J Pharm Bioallied Sci. 2017 Nov;9(Suppl 1):S180-S186. doi: 10.4103/jpbs.JPBS_176_17.
Alveolar bone resorption is a significant clinical problem. Bone loss in third molar region following extraction or surgical removal not only leads to periodontal problems in second molar region but also it may lead to some serious problems like increased incidence of angle fractures. In order to reduce the risks following third molar surgery, the socket should be augmented with bone grafts. In recent days guided tissue regeneration is the most accepted and successful technique followed many authors and its efficacy has been proved.
Based upon our clinical experience, the use of bio absorbable collagen wound dressing such as CollaPlug has achieved quick healing and more primary wound coverage. Amongst the graft materials collagen is preferable due to its high biocompatibility and hemostatic ability. This study was done to assess the regeneration of bone in the extracted third molar sockets using xenograft (CollaPlug-Zimmer) which was compared with the normal healing on the contra lateral side. The assessment was done to analyze post-operative healing complications and to compare the bone density formed between control site and implant site radiologically.
On this basis of this study, the use of collaplugTN appears to be beneficial to the patient in postoperative wound healing and also for better bone formation. The use of this material was advantageous because of its simplicity of application cost effectiveness and availability. There is enhanced wound healing and early bone formation.
牙槽骨吸收是一个严重的临床问题。第三磨牙拔除或手术切除后的骨丢失不仅会导致第二磨牙区域的牙周问题，还可能引发一些严重问题，如角状骨折发生率增加。为降低第三磨牙手术后的风险，拔牙窝应使用骨移植材料进行填充。近年来，引导组织再生是被众多作者采用且最为成功的技术，其疗效已得到证实。
根据我们的临床经验，使用生物可吸收胶原伤口敷料（如CollaPlug）可实现快速愈合和更高的一期伤口覆盖。在移植材料中，胶原因其高生物相容性和止血能力而更受青睐。本研究旨在评估使用异种移植物（CollaPlug - Zimmer）的拔除第三磨牙牙槽窝的骨再生情况，并与对侧的正常愈合情况进行比较。评估内容包括分析术后愈合并发症，并通过影像学比较对照部位和种植部位形成的骨密度。
基于本研究，使用CollaplugTN似乎对患者术后伤口愈合以及更好的骨形成有益。使用这种材料具有优势，因为其应用简单、成本效益高且易于获取。伤口愈合得到增强，骨形成更早。
