Biospheric Assessment for Waste Disposal Team, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan; State Key Laboratory of Nuclear Physics and Technology, School of Physics, Peking University, Beijing 100871, China.
Biospheric Assessment for Waste Disposal Team, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan; Fukushima Project Headquarters, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, 4-9-1 Anagawa, Inage, Chiba 263-8555, Japan.
Anal Chim Acta. 2018 Feb 13;1000:85-92. doi: 10.1016/j.aca.2017.10.012. Epub 2017 Oct 17.
A rapid method with enhanced U decontamination was developed for ultra-trace Pu analysis in small-volume urine bioassays. This method consists of acid digestion, co-precipitation, extraction chromatography and sector-field inductively coupled plasma mass spectrometry (SF-ICP-MS) measurement. Parameters that may influence the analytical performance were studied systematically. This method achieved a high U decontamination factor (3.8 × 10) and the Pu recovery was stable for 20 mL and 100 mL urine bioassays with an average value of 72.7 ± 5.5%. The limits of detection for Pu, Pu and Pu by the method were 0.016 fg mL, 0.016 fg mL and 0.019 fg mL for 20 mL urine samples and 0.003 fg mL, 0.002 fg mL and 0.003 fg mL for 100 mL urine samples, respectively. Considering the small volume of urine employed in this study, the absolute detection limits of the method were comparable or even better than those measured with thermal ionization mass spectrometry and accelerator mass spectrometry. All procedures for 20 mL and 100 mL urine bioassays were completed in 9.5 h and 11 h, respectively, and analysis of 10 samples could be finished within one day. With the considerably low detection limits of Pu isotopes and high sample throughput, this method would be a promising tool for the quick response to radiological emergencies and for rapid screening of unexpected occupational exposures of workers involved in the future FDNPP reactor decommissioning operations.
开发了一种快速的 U 去污方法，用于小体积尿液生物测定中超痕量 Pu 的分析。该方法包括酸消解、共沉淀、萃取色谱和扇形场电感耦合等离子体质谱（SF-ICP-MS）测量。系统研究了可能影响分析性能的参数。该方法实现了高 U 去污因子（3.8×10），Pu 的回收率在 20 和 100 mL 尿液生物测定中稳定，平均值分别为 72.7±5.5%。该方法对 Pu、Pu 和 Pu 的检出限分别为 20 mL 尿液样品为 0.016 fg mL、0.016 fg mL 和 0.019 fg mL，100 mL 尿液样品为 0.003 fg mL、0.002 fg mL 和 0.003 fg mL。考虑到本研究中使用的尿液量较小，该方法的绝对检出限与热电离质谱和加速器质谱测量的检出限相当，甚至更好。20 和 100 mL 尿液生物测定的所有程序分别在 9.5 和 11 小时内完成，每天可完成 10 个样品的分析。该方法具有 Pu 同位素的低检测限和高通量的特点，是对放射紧急情况做出快速反应以及对未来福岛第一核电站反应堆退役作业中涉及的工作人员进行意外职业照射的快速筛选的有前途的工具。
