Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, 24 No. 63C-69 Carrera, Bogotá, Colombia.
Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, 24 No. 63C-69 Carrera, Bogotá, Colombia.
Joint Bone Spine. 2018 Dec;85(6):715-720. doi: 10.1016/j.jbspin.2017.12.012. Epub 2017 Dec 28.
To evaluate the relationship between resilience and clinical outcomes in patients with autoimmune rheumatic diseases.
Focus groups, individual interviews, and chart reviews were done to collect data on 188 women with autoimmune rheumatic diseases, namely rheumatoid arthritis (n=51), systemic lupus erythematosus (n=70), systemic sclerosis (n=35), and Sjögren's syndrome (n=32). Demographic, clinical, and laboratory variables were assessed including disease activity by patient reported outcomes. Resilience was evaluated by using the Brief Resilience Scale. Bivariate, multiple linear regression, and classification and regression trees were used to analyse data.
Resilience was influenced by age, duration of disease, and socioeconomic status. Lower resilience scores were observed in younger patients (<48years) with systemic lupus erythematosus, rheumatoid arthritis, and systemic sclerosis who had low socioeconomic status, whereas older patients (>50years) had higher resilience scores regardless of socioeconomic status. There was no influence of disease activity on resilience. A particular behaviour was observed in systemic sclerosis in which patients with high socioeconomic status and regular physical activity had higher resilience scores.
Resilience in patients with autoimmune rheumatic diseases is a continuum process influenced by age and socioeconomic status. The ways in which these variables along with exercise influence resilience deserve further investigation.
评估自身免疫性风湿病患者的韧性与临床结局之间的关系。
采用焦点小组、个体访谈和病历回顾，对 188 名患有自身免疫性风湿病的女性（类风湿关节炎 51 例、系统性红斑狼疮 70 例、系统性硬化症 35 例和干燥综合征 32 例）进行了数据收集。评估了包括患者报告的疾病活动度在内的人口统计学、临床和实验室变量。采用简明韧性量表评估韧性。采用双变量、多元线性回归和分类回归树对数据进行分析。
韧性受年龄、疾病持续时间和社会经济地位的影响。年轻的（<48 岁）患有系统性红斑狼疮、类风湿关节炎和系统性硬化症的患者，社会经济地位较低，其韧性评分较低，而无论社会经济地位如何，年龄较大的（>50 岁）患者的韧性评分较高。疾病活动度对韧性无影响。在系统性硬化症中观察到一种特殊的行为，即社会经济地位较高且经常进行体育锻炼的患者，其韧性评分较高。
自身免疫性风湿病患者的韧性是一个连续的过程，受年龄和社会经济地位的影响。这些变量以及运动如何影响韧性值得进一步研究。
