Khan Farhan Raza, Ahmad Tashfeen, Hussain Rabia, Bhutta Zulfiqar Ahmed
Department of Dental Surgery, The Aga Khan University and Hospital, Karachi.
Department of Orthopedic Surgery, The Aga Khan University and Hospital, Karachi.
J Coll Physicians Surg Pak. 2018 Jan;28(1):36-39. doi: 10.29271/jcpsp.2018.01.36.
To determine if low birth weight is associated with hypovitaminosis D and periodontal disease among a sample of Pakistani women residing in district Jhelum, Punjab.
Cross-sectional study nested in a large community-based longitudinal study.
Tehsil Pind Dadan Khan, District Jhelum, Pakistan from August 2012 to October 2015.
Women during 12-16th week of pregnancy were selected. Dental examination was performed. Probing depth >3 mm was labeled as periodontal disease, whereas serum level <20.0 ng/mL was taken as hypovitaminosis D. Mothers of low birth weight babies (<2500 g) were compared to mothers who gave birth to normal weight (>2500 g) babies. Odds ratio was applied to measure the strength of association of low birth weight with maternal hypovitaminosis D and also for maternal periodontal disease.
There were 62 participants in the study. The mean age of mothers was 26.7 ±4.5 years. It was alarming to observe that 53 (85%) participants had vitamin D deficiency. However, periodontal disease was only seen in four participants (6%). Out of the 62 mothers, eighteen (29%) gave birth to low birth weight babies. None of the variables were found to be associated with the low birth weight.
The present study did not find any significant association of low birth weight with hypovitaminosis D or maternal periodontal disease in the studied sample.
确定在旁遮普省杰赫勒姆地区居住的巴基斯坦女性样本中，低出生体重是否与维生素D缺乏症和牙周疾病相关。
嵌套于一项大型社区纵向研究中的横断面研究。
2012年8月至2015年10月，巴基斯坦杰赫勒姆地区平德达丹汗乡。
选取妊娠12 - 16周的女性。进行牙科检查。探诊深度>3毫米被标记为牙周疾病，而血清水平<20.0纳克/毫升被视为维生素D缺乏症。将低出生体重婴儿（<2500克）的母亲与出生正常体重（>2500克）婴儿的母亲进行比较。应用比值比来衡量低出生体重与母亲维生素D缺乏症以及母亲牙周疾病之间关联的强度。
该研究有62名参与者。母亲的平均年龄为26.7±4.5岁。令人担忧的是，53名（85%）参与者存在维生素D缺乏。然而，仅4名（6%）参与者患有牙周疾病。在62名母亲中，18名（29%）生下了低出生体重婴儿。未发现任何变量与低出生体重相关。
本研究在所研究的样本中未发现低出生体重与维生素D缺乏症或母亲牙周疾病之间存在任何显著关联。
