Stenfors L E, Räisänen S
Department of Otolaryngology, Central Hospital of Keski-Pohjanmaa, Kokkola, Finland.
Acta Otolaryngol. 1989 Jan-Feb;107(1-2):104-10. doi: 10.3109/00016488909127486.
Colonization of middle ear pathogens (S. pneumoniae, H. influenzae and B. catarrhalis) in the nasopharyngeal opening of the Eustachian tube (NO) was charted in 94 patients (170 ears) suffering from secretory otitis media (SOM). Subsequent determination of microorganisms in the middle ear effusion was performed. 76% of the patients had colonization of pathogens in the NO, while pathogens colonized the middle ear cavity (MEC) in 30% of the cases. Predominant pathogen was S. pneumoniae, followed by B. catarrhalis and H. influenzae. When colonizing the MEC, there was a 100% correlation to NO regarding B. catarrhalis, 81% correlation for S. pneumoniae and 57% for H. influenzae. S. aureus and/or coagulase-negative staphylococci were only occasionally found in the NO. Accumulation of a sticky glue effusion material in the middle ear cavity may serve as a barrier against ascending pathogens from the nasopharynx.
对94例（170耳）分泌性中耳炎（SOM）患者咽鼓管鼻咽开口处（NO）中耳病原体（肺炎链球菌、流感嗜血杆菌和卡他莫拉菌）的定植情况进行了记录。随后对中耳积液中的微生物进行了测定。76%的患者在NO处有病原菌定植，而30%的病例中病原菌定植于中耳腔（MEC）。主要病原菌为肺炎链球菌，其次是卡他莫拉菌和流感嗜血杆菌。当定植于MEC时，卡他莫拉菌与NO的相关性为100%，肺炎链球菌为81%，流感嗜血杆菌为57%。金黄色葡萄球菌和/或凝固酶阴性葡萄球菌仅偶尔在NO处发现。中耳腔内粘性胶状积液物质的积聚可能作为防止病原菌从鼻咽部上行的屏障。
