Smith D L
Am Pharm. 1989 Feb;NS29(2):42-5, 49-53. doi: 10.1016/s0160-3450(15)31856-0.
As a direct response to the profound negative impact that the high rate of noncompliance is having on therapeutic efficacy and total health-care costs, some pharmaceutical manufacturers have taken steps to develop compliance packaging for some products prescribed for ambulatory patients. The purpose of compliance packaging is to serve as a patient-education tool for health professionals and to make it easier for patients to remember to take their medications correctly at home. The ideal compliance package will be developed according to patient-education guidelines. Compliance packaging holds promise as a significant patient-education tool when health professionals combine it with personalized patient counseling and well-written medication instructions. Well-controlled cost-effectiveness studies are needed to determine the impact of compliance packaging on reducing total health-care costs.
作为对高不依从率对治疗效果和总体医疗保健成本产生的深远负面影响的直接回应，一些制药商已采取措施为门诊患者开具的某些产品开发依从性包装。依从性包装的目的是作为健康专业人员的患者教育工具，并使患者在家中更容易记住正确服药。理想的依从性包装将根据患者教育指南来开发。当健康专业人员将依从性包装与个性化的患者咨询和编写良好的用药说明相结合时，依从性包装有望成为一种重要的患者教育工具。需要进行严格控制的成本效益研究，以确定依从性包装对降低总体医疗保健成本的影响。
