Cell Biology Department, Universidade de Brasília, Distrito Federal, Brazil.
Biochemistry Laboratory, Chemistry Department, Universidade Federal de Lavras, Lavras, Minas Gerais, Brazil.
Curr Cancer Drug Targets. 2018;18(10):957-966. doi: 10.2174/1568009618666180102105843.
Essential oils are complex mixtures of low molecular weight compounds extracted from plants. Their main constituents are terpenes and phenylpropanoids, which are responsible for their biological and pharmaceutical properties, such as insecticidal, parasiticidal, antimicrobial, antioxidant, anti-inflammatory, analgesic, antinociceptive, anticarcinogenic, and antitumor properties. Cancer is a complex genetic disease considered as a serious public health problem worldwide, accounting for more than 8 million deaths annually.
The activities of prevention and treatment of different types of cancer and the medicinal potential of essential oils are addressed in this review.
Several studies have demonstrated anti-carcinogenic and antitumor activity for many essential oils obtained from various plant species. They may be used as a substitution to or in addition to conventional anti-cancer therapy. Although many studies report possible mechanisms of action for essential oils compounds, more studies are necessary in order to apply them safely and appropriately in cancer therapy.
精油是从植物中提取的低分子量化合物的复杂混合物。它们的主要成分是萜烯和苯丙烷类化合物,这些化合物决定了精油的生物学和药学特性,如杀虫、杀寄生虫、抗菌、抗氧化、抗炎、镇痛、抗伤害感受、抗癌和抗肿瘤特性。癌症是一种复杂的遗传疾病,被认为是全球严重的公共卫生问题,每年导致超过 800 万人死亡。
本综述旨在探讨不同类型癌症的预防和治疗活动以及精油的药用潜力。
多项研究表明,从多种植物物种中获得的许多精油具有抗癌和抗肿瘤活性。它们可以作为传统抗癌疗法的替代或补充。尽管许多研究报告了精油化合物的可能作用机制,但仍需要更多的研究,以便在癌症治疗中安全和适当地应用它们。