HELLP综合征患者血浆中与血管性血友病因子未结合的游离形式ADAMTS13严重减少。
Severe reduction of free-form ADAMTS13, unbound to von Willebrand factor, in plasma of patients with HELLP syndrome.
作者信息
Yoshida Yoko, Matsumoto Masanori, Yagi Hideo, Isonishi Ayami, Sakai Kazuya, Hayakawa Masaki, Hori Yuji, Sado Toshiyuki, Kobayashi Hiroshi, Fujimura Yoshihiro
机构信息
Department of Blood Transfusion Medicine, Nara Medical University, Kashihara, Japan.
Japanese Red Cross Kinki Block Blood Center, Ibaraki, Japan; and.
出版信息
Blood Adv. 2017 Aug 23;1(20):1628-1631. doi: 10.1182/bloodadvances.2017006767. eCollection 2017 Sep 12.
Abstract
Severely decreased ADAMTS13 unbound to VWF may play a key role in the pathogenesis of HELLP syndrome.A qualitative ADAMTS13 assay may be important for diagnosing HELLP syndrome.
摘要
与血管性血友病因子（VWF）未结合的ADAMTS13严重减少可能在HELLP综合征的发病机制中起关键作用。ADAMTS13定性检测对诊断HELLP综合征可能很重要。
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