计算机断层扫描评估自体脂肪注射用于声带麻痹的增容效果
Computed tomographic assessment of autologous fat injection augmentation for vocal fold paralysis.
作者信息
Nishio Naoki, Fujimoto Yasushi, Hiramatsu Mariko, Maruo Takashi, Suga Kenji, Tsuzuki Hidenori, Mukoyama Nobuaki, Shimono Mariko, Toriyama Kazuhiro, Takanari Keisuke, Kamei Yuzuru, Sone Michihiko
机构信息
Department of Otorhinolaryngology Nagoya University Graduate School of Medicine Nagoya Japan.
Department of Plastic and Reconstructive Surgery Nagoya University Graduate School of Medicine Nagoya Japan.
出版信息
Laryngoscope Investig Otolaryngol. 2017 Nov 22;2(6):459-465. doi: 10.1002/lio2.125. eCollection 2017 Dec.
OBJECTIVE
To perform a quantitative computed tomography (CT) assessment of short- and long-term outcomes of autologous fat injection augmentation in patients with unilateral vocal fold paralysis.
STUDY DESIGN
Retrospective case series.
METHODS
Twelve patients who had undergone autologous fat injection augmentation for unilateral vocal fold paralysis in our hospital between 2011 and 2015 were enrolled in this study. The autologous fat for injection was acquired from periumbilical subcutaneous tissue and was injected orally using a special-purpose laryngeal injection needle. To evaluate the injected fat at the follow-up assessments, CT was performed at several times after surgery in clinical practice. All thin-section CT images were transferred to a workstation, and the volume of the injected fat was calculated.
RESULTS
Patients comprised 6 men and 6 women with a mean age at the time of surgery of 62.9 years (range, 46-82 years). The actual injected fat volume was 1.1-2.5 ml (mean, 1.6 ml). In seven patients assessed by CT two days after surgery, the average residual rate of the injected fat was 63.9%. The mean residual rates of the injected fat were 30.0% at 3 months, 33.7% at 6 months, 29.2% at 12 months, and 32.0% at 24 months.
CONCLUSIONS
Although the injected fat volume decreased within the first three months and the residual rate of the injected fat was 30.0% at three months after injection, the residual fat volume remained at the same level for 24 months after injection.
LEVEL OF EVIDENCE
目的
对单侧声带麻痹患者自体脂肪注射填充的短期和长期疗效进行定量计算机断层扫描（CT）评估。
研究设计
回顾性病例系列研究。
方法
选取2011年至2015年期间在我院接受单侧声带麻痹自体脂肪注射填充的12例患者。注射用自体脂肪取自脐周皮下组织，使用专用喉注射针经口注射。为在随访评估中评价注射的脂肪，在临床实践中于术后多次进行CT检查。所有薄层CT图像均传输至工作站，并计算注射脂肪的体积。
结果
患者包括6名男性和6名女性，手术时平均年龄为62.9岁（范围46 - 82岁）。实际注射脂肪体积为1.1 - 2.5 ml（平均1.6 ml）。在术后2天接受CT检查的7例患者中，注射脂肪的平均残留率为63.9%。注射脂肪的平均残留率在3个月时为30.0%，6个月时为33.7%，12个月时为29.2%，24个月时为32.0%。
结论
尽管注射脂肪体积在最初三个月内减少，且注射后三个月时注射脂肪的残留率为30.0%，但注射后24个月残留脂肪体积保持在同一水平。
证据级别
4级。
Zotero 插件