Columbia University School of Nursing, New York, NY, 10032, USA.
AIDS Behav. 2018 Oct;22(10):3373-3383. doi: 10.1007/s10461-017-2014-0.
Persons living with HIV (PLWH) are living longer but experiencing more adverse symptoms associated with the disease and its treatment. This study aimed to examine the impact of a mHealth application (app) comprised of evidence-based self-care strategies on the symptom experience of PLWH. We conducted a 12-week feasibility study with 80 PLWH who were randomized (1:1) to a mHealth app, mobile Video Information Provider (mVIP), with self-care strategies for improving 13 commonly experienced symptoms in PLWH or to a control app. Intervention group participants showed a significantly greater improvement than the control group in 5 symptoms: anxiety (p = 0.001), depression (p = 0.001), neuropathy (p = 0.002), fever/chills/sweat (p = 0.037), and weight loss/wasting (p = 0.020). Participants in the intervention group showed greater improvement in adherence to their antiretroviral medications (p = 0.017) as compared to those in the control group. In this 12-week trial, mVIP was associated with improved symptom burden and increased medication adherence in PLWH.
HIV 感染者(PLWH)的寿命延长,但他们经历更多与疾病及其治疗相关的不良症状。本研究旨在探讨一款包含循证自我护理策略的移动医疗应用程序(app)对 PLWH 症状体验的影响。我们对 80 名 PLWH 进行了为期 12 周的可行性研究,他们被随机分为移动医疗应用程序(mHealth app)组和移动视频信息提供商(mVIP)组(1:1),前者包含改善 PLWH 中 13 种常见症状的自我护理策略,后者为对照组。与对照组相比,干预组在 5 种症状上的改善更为显著:焦虑(p=0.001)、抑郁(p=0.001)、神经病变(p=0.002)、发热/寒战/出汗(p=0.037)和体重减轻/消耗(p=0.020)。与对照组相比,干预组参与者在抗逆转录病毒药物的依从性上有了更大的改善(p=0.017)。在这项为期 12 周的试验中,mVIP 与 PLWH 症状负担的减轻和药物依从性的提高有关。