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移动医疗技术改善低收入 HIV 感染者的症状管理

Mobile Health Technology for Improving Symptom Management in Low Income Persons Living with HIV.

机构信息

Columbia University School of Nursing, New York, NY, 10032, USA.

出版信息

AIDS Behav. 2018 Oct;22(10):3373-3383. doi: 10.1007/s10461-017-2014-0.

Abstract

Persons living with HIV (PLWH) are living longer but experiencing more adverse symptoms associated with the disease and its treatment. This study aimed to examine the impact of a mHealth application (app) comprised of evidence-based self-care strategies on the symptom experience of PLWH. We conducted a 12-week feasibility study with 80 PLWH who were randomized (1:1) to a mHealth app, mobile Video Information Provider (mVIP), with self-care strategies for improving 13 commonly experienced symptoms in PLWH or to a control app. Intervention group participants showed a significantly greater improvement than the control group in 5 symptoms: anxiety (p = 0.001), depression (p = 0.001), neuropathy (p = 0.002), fever/chills/sweat (p = 0.037), and weight loss/wasting (p = 0.020). Participants in the intervention group showed greater improvement in adherence to their antiretroviral medications (p = 0.017) as compared to those in the control group. In this 12-week trial, mVIP was associated with improved symptom burden and increased medication adherence in PLWH.

摘要

HIV 感染者(PLWH)的寿命延长,但他们经历更多与疾病及其治疗相关的不良症状。本研究旨在探讨一款包含循证自我护理策略的移动医疗应用程序(app)对 PLWH 症状体验的影响。我们对 80 名 PLWH 进行了为期 12 周的可行性研究,他们被随机分为移动医疗应用程序(mHealth app)组和移动视频信息提供商(mVIP)组(1:1),前者包含改善 PLWH 中 13 种常见症状的自我护理策略,后者为对照组。与对照组相比,干预组在 5 种症状上的改善更为显著:焦虑(p=0.001)、抑郁(p=0.001)、神经病变(p=0.002)、发热/寒战/出汗(p=0.037)和体重减轻/消耗(p=0.020)。与对照组相比,干预组参与者在抗逆转录病毒药物的依从性上有了更大的改善(p=0.017)。在这项为期 12 周的试验中,mVIP 与 PLWH 症状负担的减轻和药物依从性的提高有关。

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