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开放获取、订阅制质谱和蛋白质组学设施的运行经验。

Operational Experience of an Open-Access, Subscription-Based Mass Spectrometry and Proteomics Facility.

机构信息

The Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia.

出版信息

J Am Soc Mass Spectrom. 2018 Mar;29(3):439-446. doi: 10.1007/s13361-017-1862-1. Epub 2018 Jan 3.

DOI:10.1007/s13361-017-1862-1
PMID:29299836
Abstract

This paper discusses the successful adoption of a subscription-based, open-access model of service delivery for a mass spectrometry and proteomics facility. In 2009, the Mass Spectrometry and Proteomics Facility at the University of Melbourne (Australia) moved away from the standard fee for service model of service provision. Instead, the facility adopted a subscription- or membership-based, open-access model of service delivery. For a low fixed yearly cost, users could directly operate the instrumentation but, more importantly, there were no limits on usage other than the necessity to share available instrument time with all other users. All necessary training from platform staff and many of the base reagents were also provided as part of the membership cost. These changes proved to be very successful in terms of financial outcomes for the facility, instrument access and usage, and overall research output. This article describes the systems put in place as well as the overall successes and challenges associated with the operation of a mass spectrometry/proteomics core in this manner. Graphical abstract ᅟ.

摘要

本文讨论了成功采用基于订阅的开放获取服务模式来提供质谱仪和蛋白质组学设备服务。2009 年,墨尔本大学(澳大利亚)的质谱仪和蛋白质组学设备实验室(Mass Spectrometry and Proteomics Facility)不再采用传统的按服务收费的服务提供模式。相反,该实验室采用了订阅制或会员制的开放获取服务交付模式。用户只需支付较低的年费,就可以直接操作仪器,但更重要的是,除了需要与其他所有用户共享可用的仪器时间外,没有使用次数的限制。作为会员费用的一部分,平台工作人员还提供了所有必要的培训和许多基础试剂。就设施的财务成果、仪器的使用和整体研究成果而言,这些变化被证明是非常成功的。本文描述了所采用的系统,以及以这种方式运行质谱仪/蛋白质组学核心所带来的整体成功和挑战。

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