Yun Jae Won, Noh Ji Yun, Song Joon Young, Chun Chaemin, Kim Yunju, Cheong Hee Jin
Division of Infectious Diseases, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Division of Vaccine Preventable Disease Control and National Immunization Program, Korea Centers for Disease Control and Prevention, Osong, Korea.
Infect Chemother. 2017 Dec;49(4):247-254. doi: 10.3947/ic.2017.49.4.247.
The Korean influenza national immunization program was first established as an interim program in 1997, administering the influenza vaccine to low-income elderly adults. In 2005, the program assumed its present form of providing free influenza vaccination to adults aged ≥65 years. After turning over the influenza vaccination for elderly adults to the private sectors in 2015, the influenza vaccination coverage rate among this population increased to >80%. In addition, after the 2009 H1N1 influenza epidemic crisis, the vaccine was domestically produced. By reaching a 75% vaccination coverage rate in the target groups, it was possible to put an end to the influenza pandemic and fix the shortcomings of the system that existed at that time. The influenza vaccination program, provided free of cost, was extended to include infants aged <12 months in 2016 and ≤59 months in 2017 in order to reduce the influenza burden in these populations. However, the vaccine effectiveness remains low despite the high vaccination rates in elderly adults. Therefore, several areas, such as the adoption of quadrivalent influenza vaccine, adjuvanted influenza vaccine, and high-dose influenza vaccine and the expansion of vaccination target groups, still need to be addressed.
韩国国家流感免疫规划最初于1997年作为一项临时规划设立,为低收入老年人接种流感疫苗。2005年,该规划形成了目前为65岁及以上成年人提供免费流感疫苗接种的形式。2015年将老年人流感疫苗接种工作移交给私营部门后,该人群的流感疫苗接种率提高到了80%以上。此外,在2009年甲型H1N1流感疫情危机之后,开始进行疫苗的国内生产。通过在目标人群中达到75%的疫苗接种率,得以结束流感大流行并弥补当时存在的系统缺陷。为减轻这些人群的流感负担,免费提供的流感疫苗接种规划在2016年扩大到包括12月龄以下婴儿,并在2017年扩大到包括59月龄及以下儿童。然而,尽管老年人的疫苗接种率很高,但疫苗效力仍然较低。因此,仍需解决几个方面的问题,如采用四价流感疫苗、佐剂流感疫苗和高剂量流感疫苗以及扩大疫苗接种目标人群。