Wang Wenxiang, Zhang Baihua, Li Xu, Wu Jie, Wu Zhining, Ding Yan, Yang Desong, Tang Jinming, Su Min, Ma Junliang, You Xianman, Liang Jianping, Zhou Yong
The 2nd Department of Thoracic Surgery, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan Province, China.
Int J Surg Oncol (N Y). 2017 Dec;2(11):e45. doi: 10.1097/IJ9.0000000000000045. Epub 2017 Nov 8.
Minimally invasive esophagectomy (MIE) is increasingly used for the treatment of esophageal cancer. However, MIE via the Sweet approach has seldom been reported owing to the challenging procedure for a mediastinal lymph node. Thus, the approach of MIE via left-sided thoracoscopy coupled with video-assisted cervical mediastinoscopy (MIE-SM) was explored for eradicating the mediastinal lymph nodes and recurrent laryngeal nerve; the incidence of perioperative complications, mortality, and surgical radicality were analyzed.
Thirty patients with esophageal carcinoma underwent MIE-SM between June 2014 and February 2016. The primary outcome was postoperative morbidity within 2 weeks postsurgery. The secondary outcome was surgical radicality, including the circumferential margins, and the number of lymph nodes dissected.
The MIE-SM was completed in all patients within 367.6±68.7 minutes. The incidences of postoperative morbidities including pulmonary complications, anastomotic leakage, chylothorax, or recurrent nerve injury were 43.3%.
The MIE-SM was utilized for the first time to reduce the disadvantage of purely Sweet and McKeown approach, with favorable efficacy in the mediastinal and laryngeal recurrent nerve lymph node eradication. Thus, MIE-SM might be a promising alternative approach in treating esophageal cancer in selected patients.
微创食管切除术(MIE)越来越多地用于治疗食管癌。然而,由于纵隔淋巴结手术具有挑战性,经Sweet入路的MIE鲜有报道。因此,探索了通过左侧胸腔镜联合电视辅助颈部纵隔镜检查(MIE-SM)的MIE入路来清除纵隔淋巴结和喉返神经;分析围手术期并发症的发生率、死亡率和手术根治性。
2014年6月至2016年2月期间,30例食管癌患者接受了MIE-SM手术。主要结局是术后2周内的术后发病率。次要结局是手术根治性,包括切缘和清扫的淋巴结数量。
所有患者均在367.6±68.7分钟内完成了MIE-SM手术。术后并发症的发生率,包括肺部并发症、吻合口漏、乳糜胸或喉返神经损伤,为43.3%。
首次采用MIE-SM来减少单纯Sweet和McKeown入路的缺点,在纵隔和喉返神经淋巴结清除方面疗效良好。因此,MIE-SM可能是治疗部分食管癌患者的一种有前景的替代方法。