Fordham J N, Maitra S
Department of Rheumatology, Middlesbrough General Hospital, Cleveland, England.
Ann Rheum Dis. 1989 Feb;48(2):139-42. doi: 10.1136/ard.48.2.139.
Four cases of post-yersinial reactive arthritis are described. All patients presented with an acute lower limb arthropathy with features of an associated enthesopathy. Two patients had restriction of axial skeletal movements. Systemic features were prominent in three, including weight loss and malaise. Mean age of onset was 34 years. Three patients gave a history of antecedent diarrhoea within the previous month. Three patients had raised titres to Y enterocolitica type 0:3 (ranging from 1 in 320 to 1 in 2560) and one had raised titres to Y pseudotuberculosis type 2 at 1 in 640. Two of the three patients with Y enterocolitica reactive arthritis ran a chronic course with low grade arthropathy of lower limbs and back stiffness. One patient developed radiological sacroiliitis at two years, and two patients had an increased sacroiliac index, though x rays of the sacroiliac joints were normal. The patient with Y pseudotuberculosis reactive arthritis had a self limiting disease with spontaneous resolution over six months.
本文描述了4例耶尔森菌感染后反应性关节炎病例。所有患者均表现为急性下肢关节病,并伴有附着点病的特征。2例患者出现轴向骨骼运动受限。3例患者全身症状明显,包括体重减轻和不适。平均发病年龄为34岁。3例患者有前1个月内腹泻史。3例患者抗小肠结肠炎耶尔森菌0:3型抗体滴度升高(范围从1:320至1:2560),1例患者抗假结核耶尔森菌2型抗体滴度升高至1:640。3例小肠结肠炎耶尔森菌反应性关节炎患者中的2例病程呈慢性,表现为下肢低度关节病和背部僵硬。1例患者在2年后出现放射性骶髂关节炎,2例患者骶髂关节指数增加,尽管骶髂关节X线检查正常。假结核耶尔森菌反应性关节炎患者病情呈自限性,6个月内自行缓解。