Jones W G, Madden M, Finkelstein J, Yurt R W, Goodwin C W
Department of Surgery, New York Hospital-Cornell Medical Center, New York.
Ann Surg. 1989 Apr;209(4):471-4. doi: 10.1097/00000658-198904000-00013.
The use of tracheostomies in burned patients with inhalation injuries is now reserved for specific indications rather than as prophylactic airway management. A 5-year burn center experience with tracheostomies used in this fashion is presented. Ninety-nine tracheostomies were performed in 3246 patients who had indications of prolonged respiratory failure or acute loss of airway. Although colonization of the sputum was universal, neither rates of pulmonary sepsis nor mortality were significantly increased in patients who underwent tracheostomies. Twenty-eight patients developed late upper airway sequelae, including tracheal stenosis (TS), tracheoesophageal fistula (TEF), and tracheoarterial fistula (TAF). Duration of intubation correlated only with development of TAF, whereas patients in whom TEF developed were significantly older and more likely to have evidence of tracheal necrosis at the time of tracheostomy. The pathogenesis of upper airway sequelae in these patients as divergent responses to the combined insults of inhalation injury, infection, and intubation is considered.
对于吸入性损伤的烧伤患者,气管切开术目前仅用于特定指征,而非作为预防性气道管理措施。本文介绍了一家烧伤中心5年来以这种方式使用气管切开术的经验。在3246例有延长呼吸衰竭指征或气道急性丧失的患者中进行了99次气管切开术。尽管痰液定植普遍存在,但接受气管切开术的患者肺部脓毒症发生率和死亡率均未显著增加。28例患者出现晚期上气道后遗症,包括气管狭窄(TS)、气管食管瘘(TEF)和气管动脉瘘(TAF)。插管时间仅与TAF的发生相关,而发生TEF的患者年龄明显更大,且在气管切开时更可能有气管坏死的证据。本文考虑了这些患者上气道后遗症的发病机制,认为是对吸入性损伤、感染和插管等综合损伤的不同反应。