Benamar Houari, Rarivoson Elonge, Tomassini Lamberto, Frezza Claudio, Marouf Abderrazak, Bennaceur Malika, Nicoletti Marcello
a Department of Biology , University of Mostaganem Abdelhamid Ibn Badis , Mostaganem , Algeria.
b Department of Biology , University of Oran 1 Ahmed Benbella , Oran , Algeria.
Nat Prod Res. 2019 May;33(10):1456-1462. doi: 10.1080/14786419.2017.1422182. Epub 2018 Jan 5.
In this work, the extracts obtained with different solvents from the leaves of subsp. (L.) Jahand. & Maire were studied for their phytochemical profile and then for their antioxidant and acetylcholinesterase inhibitory activities. The phytochemical profiles of the extracts in -hexane, dichloromethane, ethyl acetate, methanol, anthraquinone rich and water, showed the presence of different compounds belonging to several classes of natural products such as flavonoids, anthraquinones, saccharides and fatty acids. For what concerns the biological tests, the ethyl acetate, methanol and anthraquinone rich extracts showed the highest activities in both assays due to the high amount of compounds possessing those properties such as flavonoids and anthraquinones. By consequence, these specific extracts of the species may be considered to be potential sources of natural antioxidant and anti-acetylcholinesterasic compounds.
在本研究中，对从subsp. (L.) Jahand. & Maire的叶子中用不同溶剂提取得到的提取物进行了植物化学特征研究，随后研究了其抗氧化和乙酰胆碱酯酶抑制活性。用正己烷、二氯甲烷、乙酸乙酯、甲醇、富含蒽醌的提取物以及水提取得到的提取物的植物化学特征表明，存在属于几类天然产物的不同化合物，如黄酮类化合物、蒽醌类化合物、糖类和脂肪酸。关于生物测试，乙酸乙酯、甲醇和富含蒽醌的提取物在两种测定中均表现出最高活性，这是由于含有黄酮类化合物和蒽醌类化合物等具有这些特性的化合物数量较多。因此，该物种的这些特定提取物可被视为天然抗氧化剂和抗乙酰胆碱酯酶化合物的潜在来源。
